Norfentanyl Hydrochloride

Base Information

• Chemical Name: Norfentanyl Hydrochloride
• CAS No.: 22352-81-4
• Molecular Formula: C14H20N2O.ClH
• Molecular Weight: 268.78234
• Hs Code.: 2933399090
• Mol file: 22352-81-4.mol

Synonyms:Norfentanyl Hydrochloride;4-(N-Propionanilido)piperidine Hydrochloride;N-[Piperidin-4-yl]-N-phenylpropionaMide Hydrochloride;N-4-Piperidylpropionanilide Hydrochloride;N-Phenyl-N-(4-piperidinyl)propanaMide Hydrochloride;N-Phenyl-N-4-piperidinylpropionaMide Hydrochloride

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Norfentanyl Hydrochloride

Chemical Property:

• PSA: 32.34000
• LogP: 3.31240
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Major hepatic metabolite of Fentanyl (F274990).

Technology Process of Norfentanyl Hydrochloride

There total 3 articles about Norfentanyl Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(1-benzyl-4-piperidinyl)-N-phenylpropionamide (1474-02-8) → N-(4-Piperidyl)-N-phenylpropanamide Hydrochloride (22352-81-4)

Guidance literature:

N-(1-benzyl-4-piperidinyl)-N-phenylpropionamide; With palladium on activated charcoal; hydrogen;

With hydrogenchloride; In water;

DOI:10.1002/anie.201309633

Reference yield:

1-phenylmethyl-4-piperidone (3612-20-2) → N-(4-Piperidyl)-N-phenylpropanamide Hydrochloride (22352-81-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium tris(acetoxy)borohydride

2: palladium on activated charcoal; hydrogen

With palladium on activated charcoal; hydrogen; sodium tris(acetoxy)borohydride;

DOI:10.1002/anie.201309633

Reference yield:

aniline (62-53-3) → N-(4-Piperidyl)-N-phenylpropanamide Hydrochloride (22352-81-4)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium tris(acetoxy)borohydride

2: palladium on activated charcoal; hydrogen

With palladium on activated charcoal; hydrogen; sodium tris(acetoxy)borohydride;

DOI:10.1002/anie.201309633

upstream raw materials:

N-(1-benzyl-4-piperidinyl)-N-phenylpropionamide

1-phenylmethyl-4-piperidone

aniline

Downstream raw materials:

C₂₈H₃₂N₄O

Refernces