(S)-6-(p-Bromophenyl)-2,3,5,6-tetrahydroimidazo(2,1-b)thiazole oxalate

Base Information

• Chemical Name: (S)-6-(p-Bromophenyl)-2,3,5,6-tetrahydroimidazo(2,1-b)thiazole oxalate
• CAS No.: 62284-79-1
• Molecular Formula: C13H13BrN2O4S
• Molecular Weight: 373.22
• DSSTox Substance ID: DTXSID10977850
• ChEMBL ID: CHEMBL3244728
• Mol file: 62284-79-1.mol

Synonyms:(S)-6-(p-Bromophenyl)-2,3,5,6-tetrahydroimidazo(2,1-b)thiazole oxalate;(-)-p-Bromotetramisole oxalate;(-)-4-Bromotetramisole oxalate;6-(4-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole;oxalic acid;(S)-(-)-4-Bromotetramisole Oxalate;(-)-4-bromotetramisole oxalate salt;(-)-p-Bromolevamisole oxalate;EINECS 263-487-0;CHEMBL3244728;DTXSID10977850;HMS3370I15;HMS3653I20;MFCD00070406;6-(4-bromophenyl)-2H,3H,5H,6H-imidazo[2,1-b][1,3]thiazole;AKOS015914047;SY273071;FT-0640818;EN300-12476301;(6S)-6-(4-bromophenyl)-2,3,5,6-tetrahydroimidazo[2,1-b][1,3]thiazole;Imidazo(2,1-b)thiazole, 6-(4-bromophenyl)-2,3,5,6-tetrahydro-, (S)-, ethanedioate (1:1);6646-52-2

Chemical Property of (S)-6-(p-Bromophenyl)-2,3,5,6-tetrahydroimidazo(2,1-b)thiazole oxalate

Chemical Property:

• Appearance/Colour: white to light yellow crystal powder
• Vapor Pressure: 3.03E-06mmHg at 25°C
• Melting Point: 192 °C (dec. )
• Boiling Point: 388.6 °C at 760 mmHg
• Flash Point: 188.8 °C
• PSA: 115.50000
• LogP: 1.43770
• Storage Temp.: 2-8°C
• Solubility.: Soluble in Water (up to 10 mg/ml)
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 2
• Exact Mass: 371.97794
• Heavy Atom Count: 21
• Complexity: 345

Purity/Quality:

99% ^*data from raw suppliers

(-)-p-BromotetramisoleOxalate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn
• Statements: 21/22-36/37/38-20/21/22
• Safety Statements: 24/25-36/37/39-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1CSC2=NC(CN21)C3=CC=C(C=C3)Br.C(=O)(C(=O)O)O
• Description: Four distinct human isoenzymes of alkaline phosphatase (AP) are known: intestinal (IAP), placental (PLAP), tissue non-specific (NSAP, also known as liver/bone/kidney AP), and germ cell AP (also known as placental-like AP, PLAP-like). L-p-Bromotetramisole is a cell-permeable inhibitor of all four human AP isoenzymes (Kis =18 and 56 μM for PLAP and NSAP, respectively). While PLAP is strongly inhibited by L-p-bromotetramisole, a second AP, possibly PLAP-like, shows only partial inhibition. L-p-Bromotetramisole has been shown to inhibit a tyrosine phosphatase from Drosophila and, as a result, is also used as a tyrosine phosphatase inhibitor.
• Uses: L-p-Bromotetramisole Oxalate or (-)-p-Bromotetramisole Oxalate is a potent inhibitor of alkaline phosphatase.