Technology Process of 3-Hydroxytricyclo[3.3.1.13,7]decane-1-carboxaldehyde
There total 4 articles about 3-Hydroxytricyclo[3.3.1.13,7]decane-1-carboxaldehyde which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
3-hydroxy-1-adamantanecarbonitrile;
With
hydrogenchloride; tin(ll) chloride;
In
diethyl ether;
at 0 - 25 ℃;
for 22h;
With
water;
In
diethyl ether;
at 20 - 60 ℃;
DOI:10.1023/A:1013178326353
- Guidance literature:
-
With
sodium hypochlorite; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hydrogencarbonate; potassium bromide;
In
dichloromethane; water;
at 0 - 5 ℃;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: sulfuric acid; nitric acid; water / -5 - 1 °C
2.1: sodium tetrahydroborate / tetrahydrofuran / 2.5 h / 0 - 31 °C
2.2: 14.5 h / 0 - 30 °C
2.3: 1 h / 0 - 10 °C
3.1: potassium bromide; sodium hydrogencarbonate; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sodium hypochlorite / dichloromethane; water / 0 - 5 °C
With
sodium hypochlorite; sodium tetrahydroborate; 2,2,6,6-Tetramethyl-1-piperidinyloxy free radical; sulfuric acid; water; nitric acid; sodium hydrogencarbonate; potassium bromide;
In
tetrahydrofuran; dichloromethane; water;
