7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dod ecahydro-11-hydroxy-6-methoxy-4a,8,13,13-tetramethyl-4,9-bis[(triethyl silyl)oxy]-, [2aR-(2aa,4b,4ab,6b,9a,11a,12a,12aa,12ba)]-

Base Information Edit

Chemical Name:7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dod ecahydro-11-hydroxy-6-methoxy-4a,8,13,13-tetramethyl-4,9-bis[(triethyl silyl)oxy]-, [2aR-(2aa,4b,4ab,6b,9a,11a,12a,12aa,12ba)]-
CAS No.:183133-98-4
Molecular Formula:C42H66O10Si2
Molecular Weight:787.151
Hs Code.:
Mol file:183133-98-4.mol

7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dod ecahydro-11-hydroxy-6-methoxy-4a,8,13,13-tetramethyl-4,9-bis[(triethyl silyl)oxy]-, [2aR-(2aa,4b,4ab,6b,9a,11a,12a,12aa,12ba)]-

Synonyms:

Suppliers and Price of 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dod ecahydro-11-hydroxy-6-methoxy-4a,8,13,13-tetramethyl-4,9-bis[(triethyl silyl)oxy]-, [2aR-(2aa,4b,4ab,6b,9a,11a,12a,12aa,12ba)]-

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dod ecahydro-11-hydroxy-6-methoxy-4a,8,13,13-tetramethyl-4,9-bis[(triethyl silyl)oxy]-, [2aR-(2aa,4b,4ab,6b,9a,11a,12a,12aa,12ba)]- Edit

Chemical Property:

Purity/Quality:: 98.5% ^*data from raw suppliers

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Technology Process of 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dod ecahydro-11-hydroxy-6-methoxy-4a,8,13,13-tetramethyl-4,9-bis[(triethyl silyl)oxy]-, [2aR-(2aa,4b,4ab,6b,9a,11a,12a,12aa,12ba)]-

There total 3 articles about 7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxet-5-one, 12b-(acetyloxy)-12-(benzoyloxy)-1,2a,3,4,4a,6,9,10,11,12,12a,12b-dod ecahydro-11-hydroxy-6-methoxy-4a,8,13,13-tetramethyl-4,9-bis[(triethyl silyl)oxy]-, [2aR-(2aa,4b,4ab,6b,9a,11a,12a,12aa,12ba)]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.7%

: 183133-99-5
4α-acetoxy-2α-benzoyloxy-5β,20-epoxy-1β,10β-dihydroxy-9-oxo-7β,13α-di(triethylsilyloxy)-11-taxene

: 74-88-4
methyl iodide

: 183133-98-4
4α-acetoxy-2α-benzoyloxy-5β,20-epoxy-1β-hydroxy-9-oxo-10β-methoxy-7β,13α-di(triethylsilyloxy)-11-taxene

Guidance literature:: With sodium hydride; In tetrahydrofuran; at -5 - 0 ℃;

Reference yield:

: 32981-86-5,172018-16-5
10-deacetylbaccatin III

: 183133-98-4
4α-acetoxy-2α-benzoyloxy-5β,20-epoxy-1β-hydroxy-9-oxo-10β-methoxy-7β,13α-di(triethylsilyloxy)-11-taxene

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; 1H-imidazole / dichloromethane / 0 - 20 °C / Inert atmosphere

2: sodium hydride / tetrahydrofuran / -5 - 0 °C

With 1H-imidazole; dmap; sodium hydride; In tetrahydrofuran; dichloromethane;

Reference yield:

: 994-30-9
triethylsilyl chloride

: 183133-98-4
4α-acetoxy-2α-benzoyloxy-5β,20-epoxy-1β-hydroxy-9-oxo-10β-methoxy-7β,13α-di(triethylsilyloxy)-11-taxene

Guidance literature:: Multi-step reaction with 2 steps

1: dmap; 1H-imidazole / dichloromethane / 0 - 20 °C / Inert atmosphere

2: sodium hydride / tetrahydrofuran / -5 - 0 °C

With 1H-imidazole; dmap; sodium hydride; In tetrahydrofuran; dichloromethane;