1H-Pyrazolo[3,4-c]pyridine-5-carboxylic acid

Base Information

• Chemical Name: 1H-Pyrazolo[3,4-c]pyridine-5-carboxylic acid
• CAS No.: 1256824-45-9
• Molecular Formula: C7H5N3O2
• Molecular Weight: 163.1335
• Hs Code.: 2933990090
• Mol file: 1256824-45-9.mol

Synonyms:1H-Pyrazolo[3,4-c]pyridine-5-carboxylic acid...;

Chemical Property of 1H-Pyrazolo[3,4-c]pyridine-5-carboxylic acid

Chemical Property:

• PSA: 78.87000
• LogP: 0.65610

Purity/Quality:

98%min ^*data from raw suppliers

1H-pyrazolo[3,4-c]pyridine-5-carboxylicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-Pyrazolo[3,4-c]pyridine-5-carboxylic acid

There total 1 articles about 1H-Pyrazolo[3,4-c]pyridine-5-carboxylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl 1H-pyrazolo[3,4-c]pyridine-5-carboxylate (1033772-26-7) → C7H5N3O2 (1256824-45-9)

Guidance literature:

methyl 1H-pyrazolo[3,4-c]pyridine-5-carboxylate; With lithium hydroxide; water; In methanol; at 20 ℃; for 3h;

With hydrogenchloride; In methanol; diethyl ether;

Reference yield:

C7H5N3O2 (1256824-45-9) + [4-(benzenesulfonyl)phenyl]methanamine (94341-56-7) → C20H16N4O3S (1362159-57-6)

Guidance literature:

With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; at 25 ℃;

DOI:10.1016/j.bmcl.2013.08.074

upstream raw materials:

methyl 1H-pyrazolo[3,4-c]pyridine-5-carboxylate

Downstream raw materials:

C₂₀H₁₆N₄O₃S

Refernces