1-Chloro-3-fluoropropane

Base Information

• Chemical Name: 1-Chloro-3-fluoropropane
• CAS No.: 462-38-4
• Molecular Formula: C3H6ClF
• Molecular Weight: 96.532
• DSSTox Substance ID: DTXSID40870542
• Nikkaji Number: J568.508G
• Mol file: 462-38-4.mol

Synonyms:1-chloro-3-fluoropropane;1-Fluoro-3-chloropropane;462-38-4;1-chloro-3-fluoro-propane;HCFC-271fa;DTXSID40870542;PFDZQZAOZNELDX-UHFFFAOYSA-N;AKOS006385699;F88015

Chemical Property of 1-Chloro-3-fluoropropane

Chemical Property:

• Refractive Index: 1.3871
• Boiling Point: 69.68°C (estimate)
• PSA: 0.00000
• Density: 1.0581 (estimate)
• LogP: 1.58480
• XLogP3: 1.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 96.0142060
• Heavy Atom Count: 5
• Complexity: 16.4

Purity/Quality:

98%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CF)CCl
• Uses: 1-fluoro-3-chloropropane is a hydrocarbon derivative and can be used as an intermediate in organic synthesis.

Technology Process of 1-Chloro-3-fluoropropane

There total 5 articles about 1-Chloro-3-fluoropropane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-chloro-1-propanol methansulphonate (4239-16-1) → 1-chloro-3-fluoro-propane (462-38-4)

Guidance literature:

With potassium fluoride; diethylene glycol; at 100 ℃; under 320 Torr;

DOI:10.1139/v56-099

Reference yield:

1,3-Dichloropropane (142-28-9) → 1-chloro-3-fluoro-propane (462-38-4)

Guidance literature:

With potassium fluoride; diethylene glycol; at 130 ℃;

DOI:10.1111/j.1365-2621.2001.tb11339.x

Reference yield:

3-fluoropropane-1-ol (462-43-1) → 1-chloro-3-fluoro-propane (462-38-4)

Guidance literature:

With phosphorus pentachloride;

DOI:10.1021/jo01148a031

upstream raw materials:

3-fluoropropane-1-ol

3-chloro-1-propanol methansulphonate

1,3-Dichloropropane

(3-chloropropoxy)trimethylsilane

Downstream raw materials:

diphenylether

Refernces