CNX-774

Base Information

• Chemical Name: CNX-774
• CAS No.: 1202759-32-7
• Molecular Formula: C26H22FN7O3
• Molecular Weight: 499.4963832
• Mol file: 1202759-32-7.mol

Synonyms:CNX-774;4-[4-[[5-Fluoro-4-[[3-[(1-oxo-2-propen-1-yl)amino]phenyl]amino]-2-pyrimidinyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide;4-(4-((4-((3-acrylamidophenyl)amino)-5-fluoropyrimidin-2-yl)amino)phenoxy)-N-methylpicolinamide;4-[4-[[5-Fluoro-4-[[3-[(1-oxo-2-propen-1-yl)amino]phenyl]amino]-2-pyrimidinyl]amino]phenoxy]-N-methyl-2-pyridinecarboxamide CNX-774

Chemical Property of CNX-774

Chemical Property:

• PKA: 13.22±0.70(Predicted)
• PSA: 136.88000
• Density: 1.383±0.06 g/cm3(Predicted)
• LogP: 5.30960
• Solubility.: Soluble in DMSO

Purity/Quality:

98%,99%, ^*data from raw suppliers

CNX-774 ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: CNX-774 is an irreversible, orally active, and highly selective inhibitor of Bruton’s tyrosine kinase (BTK) and can be used for the treatment of rheumatoid arthritis (RA).

Technology Process of CNX-774

There total 1 articles about CNX-774 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ CNX-774 (1202759-32-7)

Guidance literature:

Refernces