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Rheinanthrone

Base Information Edit
  • Chemical Name:Rheinanthrone
  • CAS No.:480-09-1
  • Molecular Formula:C15H10O5
  • Molecular Weight:270.241
  • Hs Code.:
  • NSC Number:658580
  • UNII:0YQK3WBH32
  • DSSTox Substance ID:DTXSID10197374
  • Nikkaji Number:J366.828B
  • Wikidata:Q16888506
  • Metabolomics Workbench ID:48532
  • ChEMBL ID:CHEMBL421615
  • Mol file:480-09-1.mol
Rheinanthrone

Synonyms:rhein-9-anthrone;rheinanthrone

Suppliers and Price of Rheinanthrone
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • Rheinanthrone
  • 10mg
  • $ 130.00
Total 2 raw suppliers
Chemical Property of Rheinanthrone Edit
Chemical Property:
  • Vapor Pressure:2.26E-15mmHg at 25°C 
  • Boiling Point:602.6°Cat760mmHg 
  • Flash Point:332.3°C 
  • PSA:94.83000 
  • Density:1.571g/cm3 
  • LogP:1.93120 
  • XLogP3:2.7
  • Hydrogen Bond Donor Count:3
  • Hydrogen Bond Acceptor Count:5
  • Rotatable Bond Count:1
  • Exact Mass:270.05282342
  • Heavy Atom Count:20
  • Complexity:421
Purity/Quality:

96% *data from raw suppliers

Rheinanthrone *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:C1C2=C(C(=CC=C2)O)C(=O)C3=C1C=C(C=C3O)C(=O)O
  • Uses Rheinanthrone, is a metabolite of Sennoside A (S258805), that is used as a laxative in the treatment of constipation. In addition. it is hypothesized to induce cell proliferation and may be a potential carcinogenic agent.
Technology Process of Rheinanthrone

There total 5 articles about Rheinanthrone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With hydrogenchloride; tin(ll) chloride; In acetic acid; at 140 ℃; for 2h;
DOI:10.1248/bpb.28.1897
Guidance literature:
Multi-step reaction with 2 steps
1: rat feces suspension / H2O / 1 h / 37 °C / anaerobic incubation in pH 7.3 phosphate buffer; effect of Ca(2+), Mg(2+), pH (4 to 11), temperature (up to 80 deg C), cysteine concn. (0 to 100 mM) investigated
2: H2O / 8 h / 37 °C / anaerobic incubation with rat feces, pH 7.3 phosphate buffer
With rat feces suspension; In water;
DOI:10.1248/cpb.30.1338
Guidance literature:
In water; at 37 ℃; for 8h; Yield given; anaerobic incubation with rat feces, pH 7.3 phosphate buffer;
DOI:10.1248/cpb.30.1338
Refernces Edit
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