4-Methylumbelliferyl3-deoxy-D-glycero-a-D-galacto-2-nonulosonicacidsodiumsalt

Base Information

• Chemical Name: 4-Methylumbelliferyl3-deoxy-D-glycero-a-D-galacto-2-nonulosonicacidsodiumsalt
• CAS No.: 123269-95-4
• Molecular Formula: C₁₉H₂₁O₁₁*Na
• Molecular Weight: 448.359
• Mol file: 123269-95-4.mol

Synonyms:4-Methylumbelliferyl3-deoxy-D-glycero-a-D-galacto-2-nonulosonicacidsodiumsalt;4-Methyl-2-oxo-2H-1-benzopyran-7-yl 3-Deoxy-D-glycero-α-D-galacto-2-nonulopyranosidonic Acid MonosodiuM Salt;4-Methyl-2-oxo-2H-1-benzopyran-7-yl 3-deoxy-D-glycero-alpha-D-galacto-2-nonulopyranosidonic acid monosodium salt

Chemical Property of 4-Methylumbelliferyl3-deoxy-D-glycero-a-D-galacto-2-nonulosonicacidsodiumsalt

Chemical Property:

• PSA: 186.79000
• LogP: -2.64220

Purity/Quality:

98%min ^*data from raw suppliers

4-Methylumbelliferyl3-Deoxy-D-glycero-D-galacto-2-nonulosonicAcid,SodiumSalt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 4-Methylumbelliferyl 3-Deoxy-D-glycero-D-galacto-2-nonulosonic Acid, Sodium Salt (cas# 123269-95-4) is a compound useful in organic synthesis.

Technology Process of 4-Methylumbelliferyl3-deoxy-D-glycero-a-D-galacto-2-nonulosonicacidsodiumsalt

There total 4 articles about 4-Methylumbelliferyl3-deoxy-D-glycero-a-D-galacto-2-nonulosonicacidsodiumsalt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

benzyl (4-methylumbelliferonyl 4,5,7,8,9-penta-O-acetyl-3-deoxy-D-glycero-α-D-galacto-2-nonulopyranosid)onate (123269-92-1) → sodium (4-methylumbelliferonyl 3-deoxy-D-glycero-α-D-galacto-2-nonulopyranosid)onate (123269-95-4)

Guidance literature:

With sodium hydroxide; In methanol; for 1h; Ambient temperature;

Reference yield:

sodium 4-methylumbelliferonate (5980-33-6) → sodium (4-methylumbelliferonyl 3-deoxy-D-glycero-α-D-galacto-2-nonulopyranosid)onate (123269-95-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 66 percent / dimethylformamide / 2 h / Ambient temperature

2: 80 percent / aq. sodium hydroxide (0.1 N) / methanol / 1 h / Ambient temperature

With sodium hydroxide; In methanol; N,N-dimethyl-formamide;

Reference yield:

benzyl 2,4,5,7,8,9-hexa-O-acetyl-3-deoxy-D-glycero-β-D-galacto-2-nonulopyranosonate (121409-12-9) → sodium (4-methylumbelliferonyl 3-deoxy-D-glycero-α-D-galacto-2-nonulopyranosid)onate (123269-95-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 97 percent / acetyl chloride, hydrogen chloride / acetic acid / 18 h / Ambient temperature

2: 66 percent / dimethylformamide / 2 h / Ambient temperature

3: 80 percent / aq. sodium hydroxide (0.1 N) / methanol / 1 h / Ambient temperature

With hydrogenchloride; sodium hydroxide; acetyl chloride; In methanol; acetic acid; N,N-dimethyl-formamide;

upstream raw materials:

benzyl (4-methylumbelliferonyl 4,5,7,8,9-penta-O-acetyl-3-deoxy-D-glycero-α-D-galacto-2-nonulopyranosid)onate

sodium 4-methylumbelliferonate

benzyl 2,4,5,7,8,9-hexa-O-acetyl-3-deoxy-D-glycero-β-D-galacto-2-nonulopyranosonate

benzyl (4,5,7,8,9-penta-O-acetyl-3-deoxy-D-glycero-β-D-galacto-2-nonulopyranosyl chlorid)onate

Refernces