4-[(2,3-Dihydro-5,6-dimethoxy-1H-inden-2-yl)methyl]-1-(phenylmethyl)piperidine Hydrochloride

Base Information

• Chemical Name: 4-[(2,3-Dihydro-5,6-dimethoxy-1H-inden-2-yl)methyl]-1-(phenylmethyl)piperidine Hydrochloride
• CAS No.: 1034439-57-0
• Molecular Formula: C₂₄H₃₁NO₂*ClH
• Molecular Weight: 401.977
• Mol file: 1034439-57-0.mol

Synonyms:4-[(2,3-Dihydro-5,6-dimethoxy-1H-inden-2-yl)methyl]-1-(phenylmethyl)piperidine Hydrochloride;Deoxy Donepezil Hydrochloride;4-[(2,3-Dihydro-5,6-diMethoxy-1H-inden-2-yl)Methyl]-1-benzylpiperidineHCl;Donepezil Deoxy IMpurity;4-[(2,3-Dihydro-5,6-dimethoxy-1H-inden-2-yl)methyl]-1-(phenylmethyl)piperidine hydrochloride (1:1);Deoxy Donepezil USP Deoxy Impurity

Chemical Property of 4-[(2,3-Dihydro-5,6-dimethoxy-1H-inden-2-yl)methyl]-1-(phenylmethyl)piperidine Hydrochloride

Chemical Property:

• Melting Point: 202-205°C
• PSA: 21.70000
• LogP: 5.46080
• Storage Temp.: Refrigerator
• Solubility.: DMSO (Slightly), Methanol (Slightly), Water (Slightly, Sonicated)

Purity/Quality:

99.0% Min ^*data from raw suppliers

DeoxyDonepezilHydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: An impurity of Donepezil. An impurity of Donepezil

Technology Process of 4-[(2,3-Dihydro-5,6-dimethoxy-1H-inden-2-yl)methyl]-1-(phenylmethyl)piperidine Hydrochloride

There total 1 articles about 4-[(2,3-Dihydro-5,6-dimethoxy-1H-inden-2-yl)methyl]-1-(phenylmethyl)piperidine Hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindane (844694-84-4) → 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindane hydrochloride (1034439-57-0)

Guidance literature:

With hydrogenchloride; In methanol; dichloromethane;

DOI:10.1021/jm8001313

upstream raw materials:

2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxyindane

Refernces