Cytidine 5'-monophosphate disodium salt

Base Information

• Chemical Name: Cytidine 5'-monophosphate disodium salt
• CAS No.: 6757-06-8
• Molecular Formula: C9H12N3Na2O8P
• Molecular Weight: 367.163
• Hs Code.: 29349990
• European Community (EC) Number: 229-819-3
• UNII: 383W8FIS5C
• DSSTox Substance ID: DTXSID20217895
• Wikidata: Q27159938
• Mol file: 6757-06-8.mol

Synonyms:6757-06-8;Cytidine 5'-monophosphate disodium salt;Cytidine-5'-monophosphate disodium salt;Disodium 5'-cytidylate;Sodium ((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl phosphate;Disodium CMP;CMP disodium salt;5'-Cytidylic acid, disodium salt;Disodium 5'-CMP;5'-CMP disodium salt;Disodium 5'-cytidilate;5'-Cytidylic Acid Disodium Salt;disodium 5'-o-phosphonatocytidine;Cytidine monophosphate disodium salt;Cytidine 5'MP, disodium salt;Disodium cytidine 5'-phosphate;Disodium cytidine 5'-monophosphate;383W8FIS5C;disodium;[(2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3,4-dihydroxyoxolan-2-yl]methyl phosphate;MFCD00064355;CCRIS 7313;Cytidine 5'-(disodium phosphate);EINECS 229-819-3;NSC 20259;NSC-20259;CMP;CYTIDINE-5'-MONOPHOSPHORIC ACID,DISODIUM;UNII-383W8FIS5C;C9H12N3Na2O8P;5'-CMP 2Na;SCHEMBL859798;CHEBI:87798;DTXSID20217895;HG1346;AKOS015918518;AC-32136;AS-13118;CYTIDINE 5' MONOPHOSPHATE DISODIUM;CYTIDINE MONOPHOSPHATE DISODIUM [WHO-DD];CYTIDINE-5'-MONOPHOSPHATE, DISODIUM SALT;A852115;W-104709;Q27159938;sodium ((2R,3S,4R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxy-tetrahydrofuran-2-yl)methyl phosphate

Chemical Property of Cytidine 5'-monophosphate disodium salt

Chemical Property:

• Appearance/Colour: White crystalline powder
• Melting Point: 300 °C
• Refractive Index: 8 ° (C=2, H2O)
• Boiling Point: 678.1oC at 760 mmHg
• Flash Point: 363.9oC
• PSA: 192.83000
• Density: 2.15g/cm3
• LogP: -0.98840
• Storage Temp.: 2-8°C
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 3
• Exact Mass: 367.01573991
• Heavy Atom Count: 23
• Complexity: 520

Purity/Quality:

99% ^*data from raw suppliers

Cytidine5''-MonophosphateDisodiumSalt ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,Xi
• Hazard Codes: Xn,Xi
• Statements: 20/21/22-36/37/38
• Safety Statements: 22-24/25-37/39-36-26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CN(C(=O)N=C1N)C2C(C(C(O2)COP(=O)([O-])[O-])O)O.[Na+].[Na+]
• Isomeric SMILES: C1=CN(C(=O)N=C1N)[C@H]2[C@@H]([C@@H]([C@H](O2)COP(=O)([O-])[O-])O)O.[Na+].[Na+]
• Recent ClinicalTrials: CMP vs Fascia Iliaca Block
• Uses: Cytidine 5'-Monophosphate Disodium Salt is a salt form of Cytidine 5'-Monophosphate, a constituent of nucleic acids that has been isolated from yeast nucleic acid. Cytidine 5′-monophosphate disodium salt has been used: in nucleotide stock solutionas an ectonucleotidase (ENTase) inhibitor to probe 5′-ENTase activity in cortical neuronsin in vitro studies to estimate its effect on growth response of selected bacteria strains that dominate the piglets′ small intestine

Technology Process of Cytidine 5'-monophosphate disodium salt

There total 1 articles about Cytidine 5'-monophosphate disodium salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C9H14N4O10P2(2-)*2Na(1+) → cytidine-5'-monophosphate disodium salt (6757-06-8)

Guidance literature:

With water; zinc(II) cation; pH=5.5;

DOI:10.1038/nchem.2878

Reference yield: 1.0%

cytidine-5'-monophosphate disodium salt (6757-06-8) + Sucrose (57-50-1) → CDP-glucose (2906-23-2)

Guidance literature:

With bovine serum albumine; adenosine-5'-triphosphate Na salt; phospho(enol)pyruvate CHA-salt; tris hydrochloride; magnesium chloride; diothiothreitol; at 30 ℃; sucrose synthase, pyruvate kinase, myokinase;

DOI:10.1016/0040-4020(95)01081-5

Reference yield:

[(η6-biphenyl)(ethylenediamine)chlororuthenium(II)] hexafluorophosphate + cytidine-5'-monophosphate disodium salt (6757-06-8) → (C6H5C6H5)Ru(H2NCH2CH2NH2)OPO3CH2C4H4O(OH)2C4H2N2(NH2)(O) + (C6H5C6H5)Ru(H2NCH2CH2NH2)(OPO3CH2C4H4O(OH)2C4H2N2(NH2)(O))

Guidance literature:

With H₂O; In water; pH 7.23, 310 K, 3 d; reaction was monitored by (1)H and (31)P NMR spectroscopy; (1)H and (31)P NMR data;

DOI:10.1021/ja027719m

Downstream raw materials:

CDP-glucose

Refernces