Dimethyl toluene-2,6-dicarbamate

Base Information

• Chemical Name: Dimethyl toluene-2,6-dicarbamate
• CAS No.: 20913-18-2
• Molecular Formula: C10H12N2O4
• Molecular Weight: 238.243
• Mol file: 20913-18-2.mol

Synonyms:2-Methyl-1,3-phenylenedicarbamic acid methyl ester;Dimethyl toluene-2,6-dicarbamate;Obtucarbamate B

Chemical Property of Dimethyl toluene-2,6-dicarbamate

Chemical Property:

• PSA: 76.66000
• LogP: 2.49760

Purity/Quality:

≥98% ^*data from raw suppliers

ObtucarbamateB 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Dimethyl toluene-2,6-dicarbamate

There total 6 articles about Dimethyl toluene-2,6-dicarbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

methanol (67-56-1) + 2,6-Toluene diisocyanate (91-08-7) → toluene-2,6-bis(methyl) carbamate (20913-18-2)

Guidance literature:

for 36h; Heating;

DOI:10.1016/0584-8539(94)80158-4

Reference yield: 76.0%

methanol (67-56-1) + 2,6-toluenediamine (823-40-5) → toluene-2,6-bis(methyl) carbamate (20913-18-2)

Guidance literature:

With copper(II) oxide; at 120 ℃; for 10h; under 7500.75 Torr; Autoclave;

Reference yield:

isofraxetin 6-O-β-D-glucopyranoside → Indole-3-carboxaldehyde (487-89-8,1228547-52-1) + 5,6-dihydroxy-7-methoxycoumarin (50656-75-2) + 2-nonyl-4-hydroxyquinoline N-oxide (55396-45-7) + isofraxidin (486-21-5) + 4,4'-dianisylmethane (726-18-1) + 2,4'-dimethoxydiphenylmethane (30567-87-4) + 1-(6-hydroxy-2,3-dimethoxyphenyl)ethan-1-one (22248-13-1) + 2,4-bis(methoxycarbonylamino)toluene (6935-99-5) + toluene-2,6-bis(methyl) carbamate (20913-18-2) + 8'-dehydroxymethyl cleomiscosin A + Benzeneacetamide (103-81-1) + gomisin N (61281-37-6,66211-88-9,69176-52-9,82467-51-4,82467-52-5,82467-53-6,82467-54-7,64121-95-5) + uracil (66-22-8,144104-68-7,18324-22-6,27072-01-1,2920-92-5,51953-19-6) + (+)-isoschizandrin + 6-methoxy-5′′-demethoxydaphneticin

Guidance literature:

With Angelica sinensis (Oliv_.) Diels callus; In methanol; for 168h;

DOI:10.1016/j.bmcl.2016.11.069

upstream raw materials:

methanol

2,6-Toluene diisocyanate

carbon monoxide

2,6-dinitrotoluene

Downstream raw materials:

2,6-Toluene diisocyanate

Refernces

• 1、 Zhou, Di,Zhang, Yuhua,Jiang, Zhe,Hou, Yue,Jiao, Kun,Yan, Chunyan,Li, Ning. "Biotransformation of isofraxetin-6-O-β-D-glucopyranoside by Angelica sinensis (Oliv.) Diels callus". . p. 248 - 253. Retrieved 2016/12/27.
• 2、 -. "ZINC CLUSTER COMPOUNDS AND THEIR USE AS CATALYSTS IN THE REACTION OF AMINES WITH DIALKYL CARBONATES". Page/Page column 12. . Retrieved 2014/12/12.