4-Phenoxybenzophenone

Base Information

• Chemical Name: 4-Phenoxybenzophenone
• CAS No.: 6317-73-3
• Molecular Formula: C19H14 O2
• Molecular Weight: 274.319
• Hs Code.: 2914509090
• European Community (EC) Number: 613-173-8
• NSC Number: 43083
• UNII: 1OH6XT406C
• DSSTox Substance ID: DTXSID00285875
• Nikkaji Number: J787.971G
• Wikidata: Q27252690
• Mol file: 6317-73-3.mol

Synonyms:4-Phenoxybenzophenone;6317-73-3;(4-phenoxyphenyl)(phenyl)methanone;4-Phenoxy benzophenone;(4-phenoxyphenyl)-phenylmethanone;Benzophenone, 4-phenoxy-;1OH6XT406C;(4-Phenoxyphenyl)phenylmethanone;UNII-1OH6XT406C;NSC 43083;NSC-43083;NSC43083;p-phenoxybenzophenone;SCHEMBL234249;DTXSID00285875;MFCD00017553;AKOS004908153;CS-0207162;FT-0636091;P1328;D92111;A834252;Q27252690

Chemical Property of 4-Phenoxybenzophenone

Chemical Property:

• Vapor Pressure: 4.56E-07mmHg at 25°C
• Melting Point: 64°C
• Boiling Point: 414.1°C at 760 mmHg
• Flash Point: 181.5°C
• PSA: 26.30000
• Density: 1.151g/cm³
• LogP: 4.70990
• Storage Temp.: 2-8°C
• XLogP3: 5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 274.099379685
• Heavy Atom Count: 21
• Complexity: 319

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-Phenoxybenzophenone ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=O)C2=CC=C(C=C2)OC3=CC=CC=C3

Technology Process of 4-Phenoxybenzophenone

There total 22 articles about 4-Phenoxybenzophenone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

diphenylether (101-84-8) + benzoic acid (65-85-0,8013-63-6) → p-phenoxybenzophenone (6317-73-3)

Guidance literature:

With pyridin-2-yl trifluoromethanesulfonate; trifluoroacetic acid; for 5h; Heating;

DOI:10.1246/bcsj.61.455

Reference yield: 96.0%

4-methyl-N-(2-(4-phenoxyphenyl)-2-phenylvinyl)benzenesulfonamide → p-phenoxybenzophenone (6317-73-3)

Guidance literature:

With oxygen; caesium carbonate; In toluene; Inert atmosphere;

DOI:10.1021/acs.joc.7b03068

Reference yield: 92.0%

1-benzyl-4-phenoxybenzene (27798-36-3) → p-phenoxybenzophenone (6317-73-3)

Guidance literature:

With dipotassium peroxodisulfate; ferrocene; iron(II) phthalocyanine; In water; acetonitrile; at 80 ℃; for 6h;

upstream raw materials:

diphenylether

benzoyl chloride

4-nitrobenzophenone

sodium phenoxide

Downstream raw materials:

(4-tert-Butylphenyl)(4-phenoxyphenyl)chlorophenylmethane

C₂₉H₂₇O

Chlor(4-phenoxyphenyl)(4-trifluormethylphenyl)phenylmethan

(4-Biphenylyl)chlor(4-phenoxyphenyl)phenylmethan

Refernces

• 1、 Arora, Aayushi,Kaushal, Jolly,Kumar, Arun,Nautiyal, Divyanshu,Oswal, Preeti,Singh, Siddhant. "Suzuki?Miyaura coupling and O?arylation reactions catalysed by palladium(II) complexes of bulky ligands bearing naphthalene core, Schiff base functionality and biarylphosphine moiety". . . Retrieved 2022/01/19.
• 2、 Kim, Hyunseok,Park, Sangjune,Baek, Yonghyeon,Um, Kyusik,Han, Gi Uk,Jeon, Da-Hye,Han, Sang Hoon,Lee, Phil Ho. "Synthesis of diaryl ketones through oxidative cleavage of the C-C double bonds in N -Sulfonyl enamides". . p. 3486 - 3496. Retrieved 2018/04/14.