[S,(+)]-2-Isopropyl-5-oxohexanoic acid methyl ester

Base Information

• Chemical Name: [S,(+)]-2-Isopropyl-5-oxohexanoic acid methyl ester
• CAS No.: 41654-22-2
• Molecular Formula: C₁₀H₁₈O₃
• Molecular Weight: 186.251
• Mol file: 41654-22-2.mol

Synonyms:(S)-2-(1-Methylethyl)-5-oxohexanoic acid methyl ester;[S,(+)]-2-Isopropyl-5-oxohexanoic acid methyl ester

Chemical Property of [S,(+)]-2-Isopropyl-5-oxohexanoic acid methyl ester

Chemical Property:

• Boiling Point: 75 - 76 °C (2 mmHg)
• PSA: 43.37000
• LogP: 1.80080

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [S,(+)]-2-Isopropyl-5-oxohexanoic acid methyl ester

There total 12 articles about [S,(+)]-2-Isopropyl-5-oxohexanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

10-Hydroxy-2,5-dimethyl-8-isopropyl-1-decalon (94428-15-6) → (-)-α-Isopropyl-γ-acetobuttersaeure-methylester (41654-22-2)

Guidance literature:

Multi-step reaction with 3 steps

2: (i) K₂CO₃, (ii) /BRN= 1098229/

3: CrO₃, Py

With pyridine; chromium(VI) oxide;

DOI:10.1016/S0040-4039(01)99241-X

Reference yield:

(+)-2-Isopropyl-5-hydroxy-capronsaeuremethylester (91009-52-8) → (-)-α-Isopropyl-γ-acetobuttersaeure-methylester (41654-22-2)

Guidance literature:

With pyridine; chromium(VI) oxide;

DOI:10.1016/S0040-4020(01)93252-1

Reference yield:

(2S,5S)-5-Hydroxy-2-isopropyl-hexanoic acid methyl ester (91009-52-8) → (-)-α-Isopropyl-γ-acetobuttersaeure-methylester (41654-22-2)

Guidance literature:

With pyridine; chromium(VI) oxide;

DOI:10.1016/S0040-4039(01)99241-X

upstream raw materials:

diazomethane

2,5-Dimethyl-8-isopropyl-Δ^9,10-1-decalon

(+)-2-Isopropyl-5-hydroxy-capronsaeuremethylester

(2S,5S)-5-Hydroxy-2-isopropyl-hexanoic acid methyl ester