di(naphthalen-1-yl)phosphine oxide

Base Information

• Chemical Name: di(naphthalen-1-yl)phosphine oxide
• CAS No.: 13440-07-8
• Molecular Formula: C20H15OP
• Molecular Weight: 302.312
• Mol file: 13440-07-8.mol

Synonyms:di(naphthalen-1-yl)phosphine oxide

Chemical Property of di(naphthalen-1-yl)phosphine oxide

Chemical Property:

• Melting Point: 164.9-165.6 °C
• Boiling Point: 513.9±33.0 °C(Predicted)
• PSA: 40.54000
• LogP: 4.50350
• Storage Temp.: Inert atmosphere,Room Temperature

Purity/Quality:

98%,99%, ^*data from raw suppliers

Di(naphthalen-1-yl)phosphineoxide 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of di(naphthalen-1-yl)phosphine oxide

There total 9 articles about di(naphthalen-1-yl)phosphine oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

1-Bromonaphthalene (90-11-9) + phosphonic acid diethyl ester (762-04-9) → di(α-naphthyl)phosphine oxide (13440-07-8)

Guidance literature:

1-Bromonaphthalene; With iodine; magnesium; In tetrahydrofuran; Inert atmosphere;

phosphonic acid diethyl ester; With sodium hydride; In tetrahydrofuran; mineral oil; at -78 - 20 ℃; Inert atmosphere;

DOI:10.1039/c0cc01301c

Reference yield: 96.0%

1-Bromonaphthalene (90-11-9) → di(α-naphthyl)phosphine oxide (13440-07-8)

Guidance literature:

1-Bromonaphthalene; With magnesium; In tetrahydrofuran; at 68 ℃; for 4h; Inert atmosphere; Schlenk technique;

With sodium hydride; phosphonic acid diethyl ester; In tetrahydrofuran; mineral oil; at 0 - 20 ℃; for 16.5h; Inert atmosphere; Schlenk technique;

DOI:10.1002/chem.201604616

Reference yield: 81.0%

sodium diethyl phosphite (2303-76-6,118080-94-7) + 1-naphthylmagnesiumbromide (703-55-9) → di(α-naphthyl)phosphine oxide (13440-07-8)

Guidance literature:

In diethyl ether;

DOI:10.1021/jo00335a020

upstream raw materials:

sodium diethyl phosphite

1-naphthylmagnesiumbromide

Diethyl phosphonate

1-Bromonaphthalene

Downstream raw materials:

(2-formylphenyl)[di(1-naphthyl)]phosphine oxide

di(naphthalen-1-yl)(phenyl)phosphine oxide

Refernces

• 1、 Gorre, Ramesh,Enagandhula, Damodar,Balasubramanian, Sridhar,Akondi, Srirama Murthy. "Visible-light-driven metal-free aerobic synthesis of highly diastereoselective phosphinoylpyrroloindoles". supporting information. p. 1354 - 1358. Retrieved 2020/03/03.
• 2、 Unoh, Yuto,Hirano, Koji,Miura, Masahiro. "Metal-Free Electrophilic Phosphination/Cyclization of Alkynes". supporting information. p. 6106 - 6109. Retrieved 2017/05/09.