10-Hydroxydecanoic acid

Base Information

• Chemical Name: 10-Hydroxydecanoic acid
• CAS No.: 1679-53-4
• Molecular Formula: C10H20O3
• Molecular Weight: 188.267
• Hs Code.: 2942000000
• European Community (EC) Number: 216-848-1
• NSC Number: 159288,15139
• UNII: NP03XO416B
• DSSTox Substance ID: DTXSID10168428
• Nikkaji Number: J195.322B
• Wikipedia: 10-Hydroxydecanoic_acid
• Wikidata: Q18343392
• RXCUI: 1368622
• Metabolomics Workbench ID: 1309
• ChEMBL ID: CHEMBL4519263
• Mol file: 1679-53-4.mol

Synonyms:10-HDAA cpd;10-hydroxydecanoic acid;10HDA cpd

Chemical Property of 10-Hydroxydecanoic acid

Chemical Property:

• Appearance/Colour: White powder crystal
• Vapor Pressure: 1.18E-05mmHg at 25°C
• Melting Point: 75-77 °C(lit.)
• Refractive Index: 1.466
• Boiling Point: 330.8 °C at 760 mmHg
• PKA: 4.78±0.10(Predicted)
• Flash Point: 168.1 °C
• PSA: 57.53000
• Density: 1.013 g/cm³
• LogP: 2.18410
• Storage Temp.: Sealed in dry,Room Temperature
• Solubility.: Chloroform (Slightly), Methanol (Slightly)
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 9
• Exact Mass: 188.14124450
• Heavy Atom Count: 13
• Complexity: 123

Purity/Quality:

10-Hydroxydecanoic acid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C(CCCCC(=O)O)CCCCO
• Uses: Reactant involved in: ? ;Synthesis of copolymers of acrylamide and sodium acryloyloxydecanoate1? ;Macrolactonization for preparation of Sansalvamide A2? ;Studies of chain length selectivity for cutinase catalyzed polycondensation reactions3? ;Ruthenium-catalyzed esterification followed by macrocyclization4? ;Synthesis of anhydrides and esters5 10-Hydroxydecanoic acid is suitable for use in a study on Novozym 435-catalyzed condensation polymerization of cis-9,10-epoxy-18-hydroxyoctadecanoic acid and its comparison with corresponding polymerization of 10-hydroxydecanoic acid.

Technology Process of 10-Hydroxydecanoic acid

There total 42 articles about 10-Hydroxydecanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

Oxacycloundecan-2-one (5579-79-3) → 10-hydroxydecanoic acid (1679-53-4)

Guidance literature:

With sodium hydroxide;

DOI:10.1021/ja00020a036

Reference yield: 92.0%

2,2,2-trichloroethyl 10-hydroxydecanoate (52633-92-8) → 10-hydroxydecanoic acid (1679-53-4)

Guidance literature:

With tellurium; sodium tetrahydroborate; In N,N-dimethyl-formamide; Ambient temperature;

DOI:10.1080/00397919808006839

Reference yield: 92.0%

10-acetoxydecanoic acid (92038-37-4) → 10-hydroxydecanoic acid (1679-53-4)

Guidance literature:

With sodium hydroxide;

DOI:10.1134/S1070427215060075

upstream raw materials:

1,10-Decanediol

10-acetoxydecanoic acid

16-hydroxy-hexadec-6-enoic acid

10-undecenoic acid

Downstream raw materials:

10--decanoic acid

10-bisbenzyloxyphosphinoyloxydecanoic acid

10-fluorodecanoic acid

10-fluorodecanoic acid ethyl ester

Refernces

• 1、 Benton,Kiess. "". . p. 470. Retrieved 1960.
• 2、 -. "METHOD AND CATALYST FOR PRODUCING ALCOHOL". Paragraph 0223-0277. . Retrieved 2021/05/14.
• 3、 -. "Novel method for synthesizing 10-hydroxydecanoic acid through catalytic cracking of castor oil at high temperature". Paragraph 0032-0054. . Retrieved 2017/08/28.