1-O,6-O-Bis(triphenylmethyl)-D-mannitol

Base Information

• Chemical Name: 1-O,6-O-Bis(triphenylmethyl)-D-mannitol
• CAS No.: 29780-94-7
• Molecular Formula: C44H42O6
• Molecular Weight: 0
• Mol file: 29780-94-7.mol

Synonyms:1-O,6-O-Bis(triphenylmethyl)-D-mannitol

Chemical Property of 1-O,6-O-Bis(triphenylmethyl)-D-mannitol

Chemical Property:

• Melting Point: 90 - 93 °C
• PSA: 99.38000
• LogP: 6.44740

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-O,6-O-Bis(triphenylmethyl)-D-mannitol

There total 4 articles about 1-O,6-O-Bis(triphenylmethyl)-D-mannitol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

mannitol (69-65-8) + trityl chloride (76-83-5) → 1,6-di-O-(triphenylmethyl)-D-mannitol (29780-94-7)

Guidance literature:

With pyridine; for 1.5h; Reflux;

DOI:10.1021/jo500645z

Reference yield: 70.0%

mannitol (69-65-8) + trityl chloride (76-83-5) → 1,6-di-O-(triphenylmethyl)-D-mannitol (29780-94-7)

Guidance literature:

In N,N-dimethyl-formamide; at 0 ℃;

DOI:10.1039/a704208f

Reference yield:

mannitol (69-65-8) → 1,6-di-O-(triphenylmethyl)-D-mannitol (29780-94-7)

Guidance literature:

upstream raw materials:

mannitol

trityl chloride

Downstream raw materials:

1.6-Ditrityl-D-mannit-2.3.4.5-tetrastearinsaeureester

2,3,4,5-tetra-O-methyl-1,6-di-O-trityl-D-mannitol

(1R,2S,3R,4R,5R,6R)-3,4,5,6-tetrakis(benzyloxy)cyclohexane-1,2-diol

(2S,3S,4S,5S,6R)-6-acetoxy-2,3,4,5-tetrakis(benzyloxy)-cyclohexanone

Refernces

• 1、 Fidalgo, Daniela M.,Kolender, Adriana A.,Varela, Oscar. "Stereoregular poly-O-methyl [m,n]-polyurethanes derived from D-mannitol". . p. 463 - 470. Retrieved 2013.
• 2、 Mabiala-Bassiloua, Charles-Gabin,Zwolinska, Magdalena,Therisod, Helene,Sygusch, Jurgen,Therisod, Michel. "Separate synthesis and evaluation of glucitol bis-phosphate and mannitol bis-phosphate, as competitive inhibitors of fructose bis-phosphate aldolases". . p. 1735 - 1737. Retrieved 2008/12/21.