1-Phenylpropan-2-ylazanium;chloride

Base Information

• Chemical Name: 1-Phenylpropan-2-ylazanium;chloride
• CAS No.: 2706-50-5
• Molecular Formula: C9H13 N . Cl H
• Molecular Weight: 171.67
• Hs Code.: 2921499090
• Mol file: 2706-50-5.mol

Synonyms:1-phenylpropan-2-ylazanium;chloride;1-Methyl-2-phenylethylammonium chloride;rac Amphetamine Hydrochloride (100 mug/mL in Methanol)

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of 1-Phenylpropan-2-ylazanium;chloride

Chemical Property:

• Melting Point: 127-129 C
• Boiling Point: 201.5°Cat760mmHg
• Flash Point: 87.4°C
• PSA: 26.02000
• Density: g/cm³
• LogP: 3.07860
• Storage Temp.: Controlled Substance, -20?C Freezer, Under Inert Atmosphere
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 171.0814771
• Heavy Atom Count: 11
• Complexity: 84.7

Purity/Quality:

Safty Information:

• Pictogram(s): T
• Hazard Codes: T
• Statements: 25
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(CC1=CC=CC=C1)[NH3+].[Cl-]
• Uses: rac Amphetamine Hydrochloride, is CNS stimulant, and an anorexic. Controlled substance (stimulant).

Technology Process of 1-Phenylpropan-2-ylazanium;chloride

There total 18 articles about 1-Phenylpropan-2-ylazanium;chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

C21H22NOP (345308-53-4) → amphetamine hydrochloride (2706-50-5,405-41-4)

Guidance literature:

With hydrogenchloride; In benzene;

DOI:10.1055/s-1982-29774

Reference yield: 72.3%

2-chloro-1-methyl-2-phenyl-ethylamine; hydrochloride (39861-30-8) → amphetamine hydrochloride (2706-50-5,405-41-4)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; under 2587.76 Torr;

Reference yield: 64.0%

diethyl (1-phenylpropan-2-yl)phosphoramidate (7761-64-0,22783-17-1) → amphetamine hydrochloride (2706-50-5,405-41-4)

Guidance literature:

With hydrogenchloride; In benzene; Ambient temperature;

DOI:10.1055/s-1982-29995

upstream raw materials:

diethyl (1-phenylpropan-2-yl)phosphoramidate

C₂₁H₂₂NOP

1-methyl-2-phenylethylmagnesium bromide

allylbenzene

Downstream raw materials:

amphetaminil

3-[(1-Methyl-2-phenyl-ethylamino)-methyl]-5-pyridin-4-yl-3H-[1,3,4]oxadiazole-2-thione; hydrochloride

4-methyl-N-(1-phenylpropan-2-yl)benzenesulfonamide

N-(1-Methyl-2-phenylethyl)harnstoff

Refernces

• 1、 Kramer, S?ren. "Synthesis of α-Substituted Primary Benzylamines through Copper-Catalyzed Cross-Dehydrogenative Coupling". supporting information. p. 65 - 69. Retrieved 2019/01/04.
• 2、 Lenstra, Danny C.,Lenting, Peter E.,Mecinovi?, Jasmin. "Sustainable organophosphorus-catalysed Staudinger reduction". . p. 4418 - 4422. Retrieved 2018/10/17.