N-Isopropyl-N-methyl-tert-butylamine

Base Information

• Chemical Name: N-Isopropyl-N-methyl-tert-butylamine
• CAS No.: 85523-00-8
• Molecular Formula: C8H19N
• Molecular Weight: 129.24
• Hs Code.: 2921199090
• European Community (EC) Number: 625-906-9
• DSSTox Substance ID: DTXSID70402936
• Nikkaji Number: J779.320K
• Wikidata: Q82206463
• Mol file: 85523-00-8.mol

Synonyms:N-Isopropyl-N-methyl-tert-butylamine;85523-00-8;N,2-dimethyl-N-propan-2-ylpropan-2-amine;N-isopropyl-N,2-dimethylpropan-2-amine;Methylisopropyl tert-butylamine;LCZC2579;SCHEMBL2047428;DTXSID70402936;n-isopropyl-n-methyl-t-butylamine;tert-butyl(methyl)(propan-2-yl)amine;AKOS025295835;N-Isopropyl-N-methyl-tert-butylamine, 98%;FT-0693758

Chemical Property of N-Isopropyl-N-methyl-tert-butylamine

Chemical Property:

• Vapor Pressure: 18.7mmHg at 25°C
• Melting Point: -76.53°C (estimate)
• Refractive Index: n20/D 1.419(lit.)
• Boiling Point: 127 °C(lit.)
• Flash Point: 49 °F
• PSA: 3.24000
• Density: 0.767 g/mL at 25 °C(lit.)
• LogP: 2.12510
• XLogP3: 2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 129.151749610
• Heavy Atom Count: 9
• Complexity: 79.1

Purity/Quality:

98%,99%, ^*data from raw suppliers

N-Isopropyl-N-methyl-tert-butylamine 98% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): F,Xi
• Hazard Codes: F,Xi
• Statements: 11-36/37/38
• Safety Statements: 16-26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)N(C)C(C)(C)C
• Uses: N-Isopropyl-N-methyl-tert-butylamine may be used to stabilize the borane-THF solutions. It may also be used for the synthesis of rotaxane, via Sonogashira coupling.

Technology Process of N-Isopropyl-N-methyl-tert-butylamine

There total 3 articles about N-Isopropyl-N-methyl-tert-butylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + N-isopropyl-N-tert-butylamine (7515-80-2) → N-isopropyl-N,2-dimethylpropan-2-amine (85523-00-8)

Guidance literature:

With formic acid; at 50 - 55 ℃; for 2h;

DOI:10.1021/jo990379b

Reference yield:

N-isopropyl-N-tert-butylamine (7515-80-2) → N-isopropyl-N,2-dimethylpropan-2-amine (85523-00-8)

Guidance literature:

DOI:10.1021/jo000638t

Reference yield:

→ N-isopropyl-N,2-dimethylpropan-2-amine (85523-00-8)

Guidance literature:

n-tert.-Butyl-N-isopropylamin, CH3J im Bombenrohr;

DOI:10.1021/ja00819a029

upstream raw materials:

formaldehyd

N-isopropyl-N-tert-butylamine

Downstream raw materials:

C₁₆H₂₃N

Refernces

• 1、 Brown, Herbert C.,Kanth, Josyula V. B.,Dalvi, Pramod V.,Zaidlewicz, Marek. "Molecular addition compounds. 15. Synthesis, hydroboration, and reduction studies of new, highly reactive tert-butyldialkylamine-borane adducts". . p. 6263 - 6274. Retrieved 2007/10/03.