2,2,3,3-Tetrafluoro-3-(trifluoromethoxy)propionic anhydride

Base Information

• Chemical Name: 2,2,3,3-Tetrafluoro-3-(trifluoromethoxy)propionic anhydride
• CAS No.: 42566-65-4
• Molecular Formula: C8F14O5
• Molecular Weight: 442.063
• Hs Code.: 2918990090
• DSSTox Substance ID: DTXSID60897579
• Wikidata: Q81983051
• Mol file: 42566-65-4.mol

Synonyms:42566-65-4;2,2,3,3-Tetrafluoro-3-(trifluoromethoxy)propionic anhydride;[2,2,3,3-tetrafluoro-3-(trifluoromethoxy)propanoyl] 2,2,3,3-tetrafluoro-3-(trifluoromethoxy)propanoate;Perfluoro-3-methoxypropanoic anhydride;MFCD20489427;2,2,3,3-Tetrafluoro-3-(trifluoromethoxy)propanoic anhydride;CID 13456324;2,2,3,3-Tetrafluoro-3-(trifluoromethoxy)propanoic acid anhydride;SCHEMBL22118451;DTXSID60897579;LVZMACBMANBCFR-UHFFFAOYSA-N;AKOS025213341;AT24550;NS00111182;2,2,3,3-Tetrafluoro-3-(trifluoromethoxy)-propionic anhydride

Chemical Property of 2,2,3,3-Tetrafluoro-3-(trifluoromethoxy)propionic anhydride

Chemical Property:

• Boiling Point: 152.9±40.0 °C(Predicted)
• PSA: 61.83000
• Density: 1.764±0.06 g/cm3(Predicted)
• LogP: 3.58520
• XLogP3: 4.9
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 19
• Rotatable Bond Count: 8
• Exact Mass: 441.9522174
• Heavy Atom Count: 27
• Complexity: 525

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C(=O)(C(C(OC(F)(F)F)(F)F)(F)F)OC(=O)C(C(OC(F)(F)F)(F)F)(F)F

Technology Process of 2,2,3,3-Tetrafluoro-3-(trifluoromethoxy)propionic anhydride

There total 2 articles about 2,2,3,3-Tetrafluoro-3-(trifluoromethoxy)propionic anhydride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 36.2%

baryum perfluoro-β-methoxypropionate (79630-78-7) → polytetrafluoroethylene (116-14-3,82785-14-6) + perfluoro-3-methoxypropionyl fluoride (425-38-7) + trifluoromethyl trifluorovinyl ether (1187-93-5) + C8F14O5 (42566-65-4)

Guidance literature:

at 240 - 300 ℃;

Reference yield: 8.6%

calcium perfluoro-β-methoxypropionate (79630-79-8) → polytetrafluoroethylene (116-14-3,82785-14-6) + perfluoro-3-methoxypropionyl fluoride (425-38-7) + trifluoromethyl trifluorovinyl ether (1187-93-5) + C8F14O5 (42566-65-4)

Guidance literature:

at 198 - 270 ℃;

Reference yield:

3,4,5-trifluoro-N-methylaniline (853767-19-8) + C8F14O5 (42566-65-4) → 2,2,3,3-tetrafluoro-N-methyl-3-(trifluoromethoxy)-N-(3,4,5-trifluorophenyl)propanamide

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide;

DOI:10.1021/acs.jafc.0c03333

upstream raw materials:

baryum perfluoro-β-methoxypropionate

calcium perfluoro-β-methoxypropionate

Refernces