3-Oxopropanamide

Base Information

• Chemical Name: 3-Oxopropanamide
• CAS No.: 5735-86-4
• Molecular Formula: C3H5NO2
• Molecular Weight: 87.0782
• NSC Number: 123371
• UNII: W7E2C7D3EW
• DSSTox Substance ID: DTXSID50298475
• Nikkaji Number: J3.561.540G
• Wikidata: Q82040305
• Mol file: 5735-86-4.mol

Synonyms:3-oxopropanamide;5735-86-4;Malonaldehydamide;Malonamaldehyde;Propanamide, 3-oxo-;Acetamide, 2-formyl-;NSC-123371;W7E2C7D3EW;formylacetamide;NSC123371;UNII-W7E2C7D3EW;DTXSID50298475;AKOS006340653;SB85407;EN300-7471147

Chemical Property of 3-Oxopropanamide

Chemical Property:

• Vapor Pressure: 0.00512mmHg at 25°C
• Boiling Point: 275.3°Cat760mmHg
• Flash Point: 120.3°C
• Density: 1.143g/cm³
• XLogP3: -1.2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 87.032028402
• Heavy Atom Count: 6
• Complexity: 69.2

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C=O)C(=O)N

Technology Process of 3-Oxopropanamide

There total 8 articles about 3-Oxopropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-asparagine (70-47-3,28088-48-4,7006-34-0) + water (7732-18-5) + hexachloroplatinate(II) (16871-54-8) → tetrachloroplatinum(II) (13965-91-8) + α-formyl acetamide (5735-86-4)

Guidance literature:

With sulfuric acid; silver nitrate; sodium sulfate; In water; at 25 ℃; for 24h; Reagent/catalyst; Kinetics; Inert atmosphere;

DOI:10.1007/s11243-015-9951-0

Reference yield:

(2-oxo-4-phenylthioazetidin-1-yl)methyl benzoate (344930-64-9) → α-formyl acetamide (5735-86-4)

Guidance literature:

With sodium hydroxide; sodium perchlorate; In water; at 25 ℃;

DOI:10.1021/jo0358123

Reference yield:

(2-oxo-4-phenylsulfonylazetidin-1-yl)methyl benzoate (344930-63-8) → α-formyl acetamide (5735-86-4)

Guidance literature:

With sodium hydroxide; sodium perchlorate; In water; at 25 ℃;

DOI:10.1021/jo0358123

upstream raw materials:

L-asparagine

ASPARAGINE

water

(2-oxo-4-phenylthioazetidin-1-yl)methyl benzoate

Downstream raw materials:

1-(para-chlorophenyl)-3-hydroxypyrazole

Refernces

• 1、 Fawzy, Ahmed. "Kinetics and mechanistic approach to the oxidative behavior of biological anticancer platinum(IV) complex toward L-asparagine in acid medium and the effect of copper(II) catalyst". . p. 1 - 12. Retrieved 2015.
• 2、 Fawzy, Ahmed. "Kinetics and Mechanistic Approach to the Oxidative Behavior of Biological Anticancer Platinum(IV) Complex toward -Asparagine in Acid Medium and the Effect of Copper(II) Catalyst". . p. 1 - 12. Retrieved 2015/08/24.