DEHYDROARIPIPRAZOLE, HYDROCHLORIDE

Base Information

• Chemical Name: DEHYDROARIPIPRAZOLE, HYDROCHLORIDE
• CAS No.: 1008531-60-9
• Molecular Formula: C₂₃H₂₅Cl₂N₃O₂*2ClH
• Molecular Weight: 519.298
• Mol file: 1008531-60-9.mol

Synonyms:DEHYDROARIPIPRAZOLE, HYDROCHLORIDE;7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-2(1H)-quinolinone Hydrochloride;7-[4-[4-(2,3-Dichlorophenyl)-1-piperazinyl]butoxy]-2(1H)-quinolinone hydrochloride (1:1)

Chemical Property of DEHYDROARIPIPRAZOLE, HYDROCHLORIDE

Chemical Property:

• Melting Point: 116-120°C
• PSA: 48.83000
• LogP: 5.23130
• Storage Temp.: -20°C Freezer
• Solubility.: Acetonitrile (Very Slightly, Heated), Methanol (Slightly)

Purity/Quality:

97% ^*data from raw suppliers

Dehydroaripiprazole, Hydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: A metabolite of Aripiprazole, a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity Dehydro Aripiprazole Hydrochloride is a metabolite of Aripiprazole, a selective dopamine D2-receptor antagonist with dopamine autoreceptor agonist activity.

Technology Process of DEHYDROARIPIPRAZOLE, HYDROCHLORIDE

There total 1 articles about DEHYDROARIPIPRAZOLE, HYDROCHLORIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

2ClH*C23H27Cl2N3O2 → 7-(4-(4-(2,3-dichlorophenyl)piperazin-1-yl)butoxy)quinolin-2-one dihydrochloride (1008531-60-9)

Guidance literature:

With sodium persulfate; iron(III) chloride hexahydrate; In water; acetonitrile; at 80 ℃; for 24h;

Refernces