8-Methoxyjulolidine, 95%

Base Information

• Chemical Name: 8-Methoxyjulolidine, 95%
• CAS No.: 63468-83-7
• Molecular Formula: C13H17NO
• Molecular Weight: 203.284
• Mol file: 63468-83-7.mol

Synonyms:8-Methoxyjulolidine, 95%

Chemical Property of 8-Methoxyjulolidine, 95%

Chemical Property:

• PSA: 12.47000
• LogP: 2.45900

Purity/Quality:

98%,99%, ^*data from raw suppliers

8-Methoxy-1,2,3,5,6,7-hexahydropyrido[3,2,1-ij]quinoline 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 8-Methoxyjulolidine, 95%

There total 5 articles about 8-Methoxyjulolidine, 95% which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

8-hydroxyjulolidine (41175-50-2) + dimethyl sulfate (77-78-1) → 8-methoxy-1,2,3,5,6,7-hexahydropyrido[3,2,1-ij]quinoline (63468-83-7)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 20 ℃; for 24h;

DOI:10.1016/j.bmcl.2008.06.065

Reference yield: 64.0%

m-Anisidine (536-90-3,918666-97-4) + 1.3-chlorobromopropane (109-70-6) → 8-methoxy-1,2,3,5,6,7-hexahydropyrido[3,2,1-ij]quinoline (63468-83-7)

Guidance literature:

With 4 A molecular sieve; sodium carbonate; a) from 70 deg C to 100 deg C, 3 h, b) reflux, 11 h;

DOI:10.1021/jo00384a015

Reference yield:

m-Anisidine (536-90-3,918666-97-4) + 1,3-dibromo-propane (109-64-8) → 8-methoxy-1,2,3,5,6,7-hexahydropyrido[3,2,1-ij]quinoline (63468-83-7)

Guidance literature:

With sodium hydroxide; at 80 - 110 ℃; for 2.5h; Industrial scale;

upstream raw materials:

m-Anisidine

1.3-chlorobromopropane

8-hydroxyjulolidine

dimethyl sulfate

Downstream raw materials:

C₂₁H₂₀N₂O₂S

C₂₁H₂₃NO₂

C₂₀H₂₀N₂O₄

10-acetyl-2,3,6,7-tetrahydro-1H-pyrano[2,3-f]pyrido[3,2,1-ij]quinoline-11(5H)-one

Refernces

• 1、 -. "Compounds and Method for Imaging Cancer". Paragraph 0041; 0098. . Retrieved 2018/10/21.
• 2、 Debnath, Tushar,Maity, Partha,Lobo, Hyacintha,Singh, Balvant,Shankarling, Ganapati S.,Ghosh, Hirendra N.. "Extensive reduction in back electron transfer in twisted intramolecular charge-transfer (TICT) coumarin-dye-sensitized TiO2 nanoparticles/film: A femtosecond transient absorption study". supporting information. p. 3510 - 3519. Retrieved 2014/04/03.