N-methyl-N-((3S,4S)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Base Information Edit

Chemical Name:N-methyl-N-((3S,4S)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine
CAS No.:384336-73-6
Molecular Formula:C13H19N5
Molecular Weight:245.327
Hs Code.:
Mol file:384336-73-6.mol

Synonyms:N-methyl-N-((3S,4S)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Suppliers and Price of N-methyl-N-((3S,4S)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 2 raw suppliers

Chemical Property of N-methyl-N-((3S,4S)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine Edit

Chemical Property:

PSA：56.84000
Density:1.197g/cm³
LogP:1.72090

Purity/Quality:: 98.5% ^*data from raw suppliers

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Technology Process of N-methyl-N-((3S,4S)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine

There total 6 articles about N-methyl-N-((3S,4S)-4-methylpiperidin-3-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 384337-90-0
methyl(1-phenylmethyl-4-methylpiperidin-3-yl)-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine

: 384336-73-6
(3R,4R)-methyl-(4-methyl-piperidin-3-yl)-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine

Guidance literature:: methyl(1-phenylmethyl-4-methylpiperidin-3-yl)-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine; With hydrogenchloride; In ethanol; water;

With hydrogen; palladium hydroxide on carbon; In ethanol; water; at 20 ℃; for 48h; under 2585.81 Torr;

Reference yield:

: 3680-69-1
4-chloro-1H-pyrrolo[2,3-d]pyrimidine

: 384336-73-6
(3R,4R)-methyl-(4-methyl-piperidin-3-yl)-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine

Guidance literature:: Multi-step reaction with 2 steps

1.1: triethylamine / 72 h / 100 °C / Sealed tube

2.1: hydrogenchloride / ethanol / Inert atmosphere

2.2: 48 h / 20 °C / 2585.81 Torr

With hydrogenchloride; triethylamine; In ethanol;

Reference yield:

: 32018-96-5
1-benzyl-4-methyl-piperidin-3-one

: 384336-73-6
(3R,4R)-methyl-(4-methyl-piperidin-3-yl)-(7H-pyrrolo[2,3-d]pyrimidin-4-yl)-amine

Guidance literature:: Multi-step reaction with 3 steps

1.1: acetic acid / tetrahydrofuran; methanol / 16 h / 20 °C / Sealed tube

1.2: 24 h / 20 °C / Sealed tube

2.1: triethylamine / 72 h / 100 °C / Sealed tube

3.1: hydrogenchloride / ethanol / Inert atmosphere

3.2: 48 h / 20 °C / 2585.81 Torr

With hydrogenchloride; acetic acid; triethylamine; In tetrahydrofuran; methanol; ethanol;