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5beta-Cholan-3alpha,7alpha,24-triol

Base Information Edit
  • Chemical Name:5beta-Cholan-3alpha,7alpha,24-triol
  • CAS No.:23848-46-6
  • Molecular Formula:C24H42O3
  • Molecular Weight:378.596
  • Hs Code.:
  • Mol file:23848-46-6.mol
5beta-Cholan-3alpha,7alpha,24-triol

Synonyms:3α,7α,24-trihydroxy-5β-cholane;CDC-OH;chenodeoxycholan-24-ol;3α,7α,24-5β-cholantriol;3α,7α,24-Trihydroxy-5β-cholan;

Suppliers and Price of 5beta-Cholan-3alpha,7alpha,24-triol
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
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Chemical Property of 5beta-Cholan-3alpha,7alpha,24-triol Edit
Chemical Property:
  • Boiling Point:509.5±25.0 °C(Predicted) 
  • PKA:14.79±0.70(Predicted) 
  • PSA:60.69000 
  • Density:1.079±0.06 g/cm3(Predicted) 
  • LogP:4.38560 
  • Storage Temp.:-20°C Freezer 
  • Solubility.:Dichloromethane; 
Purity/Quality:
Safty Information:
  • Pictogram(s):  
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MSDS Files:

SDS file from LookChem

Useful:
  • Uses Chenodeoxycholan-24-ol is an intermediate used in the synthesis of 3α,7α-Dihydroxycoprostanic Acid-d3 (D452517), which is a labelled analogue of 3α,7α-Dihydroxycoprostanic Acid (D452515), a precursor of Cholic Acid (C432600), it undergoes side chain oxidation during the synthesis of bile acids. It was found that Zellweger’s syndrome patients have abnormal mitochondrial structure, the organelle that is responsible for the side chain oxidation, and as a consequence, excess amounts of 3α,7α-Dihydroxycoprostanic Acid.
Technology Process of 5beta-Cholan-3alpha,7alpha,24-triol

There total 8 articles about 5beta-Cholan-3alpha,7alpha,24-triol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With hydrogenchloride; In methanol; water; at 20 ℃; for 2h;
DOI:10.1021/jm401873d
Guidance literature:
With methanol; lithium borohydride; In tetrahydrofuran; at 0 ℃; for 8h;
DOI:10.1021/jm401873d
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