3-(3-Thienyl)-1-propanol

Base Information

• Chemical Name: 3-(3-Thienyl)-1-propanol
• CAS No.: 20905-98-0
• Molecular Formula: C7H10OS
• Molecular Weight: 142.2187
• Hs Code.: 2934999090
• Mol file: 20905-98-0.mol

Synonyms:3-(3-Thienyl)-1-propanol;3-Thiophenepropanol

Chemical Property of 3-(3-Thienyl)-1-propanol

Chemical Property:

• Boiling Point: 244.5±15.0 °C(Predicted)
• PKA: 15.09±0.10(Predicted)
• PSA: 48.47000
• Density: 1.131±0.06 g/cm3(Predicted)
• LogP: 1.67300
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

3-(3-THIENYL)-1-PROPANOL 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(3-Thienyl)-1-propanol

There total 20 articles about 3-(3-Thienyl)-1-propanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

3-(thien-3-yl)prop-2-en-1-ol (89639-65-6) → 3-(3-thienyl)-propyl alcohol (20905-98-0)

Guidance literature:

With palladium on activated charcoal; hydrogen; at 20 ℃; for 4h;

Reference yield: 100.0%

(E)-3-(thiophen-3-yl)prop-2-en-1-ol (3216-42-0) → 3-(3-thienyl)-propyl alcohol (20905-98-0)

Guidance literature:

With palladium on activated charcoal; hydrogen; In ethanol; for 4h;

DOI:10.1016/j.tet.2011.05.009

Reference yield: 92.0%

3-(thiophen-3-yl)propanoic acid ethyl ester (99198-96-6) → 3-(3-thienyl)-propyl alcohol (20905-98-0)

Guidance literature:

With diisobutylaluminium hydride; In toluene; at 0 ℃;

DOI:10.1080/10587259408037782

upstream raw materials:

3-(3-thienyl)propanoic acid

3-(thiophen-3-yl)propanoic acid ethyl ester

3-(2-propenyl)thiophene

trimethylene oxide

Downstream raw materials:

(5R,7R)-4,5,6,7-tetrahydro-7-phenylbenzo[b]thiophene-5-carbaldehyde

(5R,7S)-4,5,6,7-tetrahydro-7-phenylbenzo[b]thiophene-5-carbaldehyde

3-((3E,7E,11E)-4,8,12,16-tetramethyl-6-(phenylsulfonyl)heptadeca-3,7,11,15-tetraen-1-yl)thiophene

C₃₆H₅₀O₂S₂

Refernces

• 1、 Sperry, Jeffrey B.,Wright, Dennis L.. "Annulated heterocycles through a radical-cation cyclization: synthetic and mechanistic studies". . p. 6551 - 6557. Retrieved 2006.
• 2、 Moustrou, Corinne,Samat, Andre,Guglielmetti, Robert,Dubest, Roger,Garnier, Francis. "Synthesis of Thiophene-Substituted Spiropyrans and Spirooxazines, Precursors of Photochromic Polymers". . p. 1887 - 1893. Retrieved 1995.
• 3、 Jayasekara, P. Suresh,Barrett, Matthew O.,Ball, Christopher B.,Brown, Kyle A.,Hammes, Eva,Balasubramanian, Ramachandran,Harden, T. Kendall,Jacobson, Kenneth A.. "4-alkyloxyimino derivatives of uridine-5′-triphosphate: Distal modification of potent agonists as a strategy for molecular probes of P2Y 2, P2Y4, and P2Y6 receptors". supporting information. p. 3874 - 3883. Retrieved 2014/05/20.
• 4、 Kotoku, Naoyuki,Fujioka, Shinichi,Nakata, Chiaki,Yamada, Masaki,Sumii, Yuji,Kawachi, Takashi,Arai, Masayoshi,Kobayashi, Motomasa. "Concise synthesis and structure-activity relationship of furospinosulin-1, a hypoxia-selective growth inhibitor from marine sponge". . p. 6673 - 6678. Retrieved 2011/09/30.