Zuretinol acetate

Base Information Edit

Chemical Name:Zuretinol acetate
CAS No.:29584-22-3
Molecular Formula:C22H32O2
Molecular Weight:328.495
Hs Code.:
UNII:2K3YP54BYU
Nikkaji Number:J701.496A
Wikidata:Q27254851
NCI Thesaurus Code:C152967
Metabolomics Workbench ID:46864
ChEMBL ID:CHEMBL4297637
Mol file:29584-22-3.mol

Synonyms:9-cis-retinyl acetate;all-trans-retinyl acetate;Dagravit A Forte;Dif Vitamin A Masivo;QLT091001;RetiNit;retinol acetate;retinol acetate, (9,13-cis)-isomer;retinyl acetate;vitamin A acetate;Vitamin A Dispersa;Vitamin-A-Saar

Suppliers and Price of Zuretinol acetate

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Medical Isotopes, Inc.
9-cis-Retinylacetate
5 mg
$ 990.00

American Custom Chemicals Corporation
9-CIS-RETINOL ACETATE 95.00%
10MG
$ 2194.50

American Custom Chemicals Corporation
9-CIS-RETINOL ACETATE 95.00%
1MG
$ 779.63

Total 11 raw suppliers

Chemical Property of Zuretinol acetate Edit

Chemical Property:

Boiling Point:440.5±14.0 °C(Predicted)
PSA：26.30000
Density:0.968±0.06 g/cm3(Predicted)
LogP:6.08110
Storage Temp.:Amber Vial, -20°C Freezer, Under Inert Atmosphere
Solubility.:Chloroform (Slightly), Ethyl Acetate
XLogP3:6.3
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:7
Exact Mass:328.240230259
Heavy Atom Count:24
Complexity:596

Purity/Quality:

98%Min ^*data from raw suppliers

9-cis-Retinylacetate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C(CCC1)(C)C)C=CC(=CC=CC(=CCOC(=O)C)C)C
Isomeric SMILES:CC1=C(C(CCC1)(C)C)/C=C/C(=C\C=C\C(=C\COC(=O)C)\C)/C
Recent ClinicalTrials:Evaluation of the Effects of Oral QLT091001 in Adults With Impaired Dark Adaptation
Recent EU Clinical Trials:A Study of the Efficacy and Safety of QLT091001 in Subjects with Inherited Retinal Disease (IRD) Caused by Mutation in Retinal Pigment Epithelium Protein 65 (RPE65) or Lecithin:Retinol Acyltransferase (LRAT)
Uses Retinal derivative for treatment of visual disorders Retinal derivative for treatment of visual disorders. Vitamin A derivative.

Technology Process of Zuretinol acetate

There total 28 articles about Zuretinol acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.7%

: 414871-77-5
C₃₆H₄₈O₆S₂

: 127-47-9,22586-94-3,29443-87-6,29444-27-7,29584-22-3,34356-31-5,63568-38-7,98462-63-6,137121-50-7,137121-51-8,137121-55-2,64536-04-5
ALK-001

Guidance literature:: With methanol; potassium hydroxide; benzyltriethylammonium chloride; In di-isopropyl ether; at 30 ℃; for 16h;

Reference yield: 91.3%

: 414871-77-5
C₃₆H₄₈O₆S₂

: 127-47-9,22586-94-3,29443-87-6,29444-27-7,29584-22-3,34356-31-5,63568-38-7,98462-63-6,137121-50-7,137121-51-8,137121-55-2,64536-04-5
(9Ξ,11Ξ,13Ξ)-O-acetyl-retinol

Guidance literature:: With methanol; potassium hydroxide; 2,6-di-tert-butyl-4-methyl-phenol; N-benzyl-N,N,N-triethylammonium chloride; In hexane; at 30 ℃; for 18h;