S-Ethyl glutathione

Base Information

• Chemical Name: S-Ethyl glutathione
• CAS No.: 24425-52-3
• Molecular Formula: C₁₂H₂₁N₃O₆S
• Molecular Weight: 335.381
• UNII: 7W95D60F4J
• DSSTox Substance ID: DTXSID40179183
• Nikkaji Number: J394.267H
• Wikidata: Q27268942
• Mol file: 24425-52-3.mol

Synonyms:gamma-glutamyl-L-cysteinylglycyl ethyl ester;glutathione ethyl ester;glutathione monoethyl ester;S-ethyl glutathione

Chemical Property of S-Ethyl glutathione

Chemical Property:

• Vapor Pressure: 4.13E-25mmHg at 25°C
• Melting Point: 150-153°C
• Boiling Point: 757.4°Cat760mmHg
• Flash Point: 411.8°C
• PSA: 184.12000
• Density: 1.362g/cm³
• LogP: 0.09930
• Storage Temp.: Hygroscopic, -20°C Freezer, Under Inert Atmosphere
• Solubility.: DMSO (Slightly), Methanol (Slightly, Sonicated), Water (Slightly)
• XLogP3: -3.8
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 11
• Exact Mass: 335.11510657
• Heavy Atom Count: 22
• Complexity: 418

Purity/Quality:

97% ^*data from raw suppliers

S-Ethylglutathione ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCSCC(C(=O)NCC(=O)O)NC(=O)CCC(C(=O)O)N
• Isomeric SMILES: CCSC[C@@H](C(=O)NCC(=O)O)NC(=O)CC[C@@H](C(=O)O)N
• Uses: An inhibitor of the enzyme Glyoxalase 1.

Technology Process of S-Ethyl glutathione

There total 2 articles about S-Ethyl glutathione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

GLUTATHIONE (70-18-8) + chloroethane (75-00-3) → S-Ethyl glutathione (24425-52-3)

Guidance literature:

With rat glutathione transferase 5-5; sodium borate buffer; at 37 ℃; for 0.0833333h; pH=8.0; Further Variations:; Reagents; Enzyme kinetics;

DOI:10.1021/tx0100183

Reference yield:

→ S-Aethylglutathion (24425-52-3)

Guidance literature:

aus Glutathion, EtI/NaOH;

DOI:10.1016/0048-3575(72)90029-6

upstream raw materials:

GLUTATHIONE

chloroethane

Refernces