2-Aminophenylarsonic acid

Base Information

• Chemical Name: 2-Aminophenylarsonic acid
• CAS No.: 2045-00-3
• Molecular Formula: C6H8 As N O3
• Molecular Weight: 217.056
• Hs Code.: 2931900038
• European Community (EC) Number: 218-064-5
• NSC Number: 12611
• UNII: 4P7T2PH7DL
• DSSTox Substance ID: DTXSID40174395
• Nikkaji Number: J7.862J
• Wikidata: Q27260326
• ChEMBL ID: CHEMBL346468
• Mol file: 2045-00-3.mol

Synonyms:o-Arsanilic acid;2-Aminophenylarsonic acid;2045-00-3;2-Aminobenzenearsonic acid;(2-aminophenyl)arsonic acid;Arsonic acid, As-(2-aminophenyl)-;2-Aminobenzinearsonic acid;UNII-4P7T2PH7DL;4P7T2PH7DL;Arsonic acid, (2-aminophenyl)-;EINECS 218-064-5;NSC-12611;2-Arsanilic acid;o-Arsanilic acid, 98%;2-Aminobenzenearsenic Acid;CHEMBL346468;SCHEMBL3264637;2-Aminophenylarsonic acid, 98%;DTXSID40174395;(O-AMINOPHENYL)ARSONIC ACID;NSC12611;MFCD00007630;NSC 12611;AKOS009031463;CS-O-30709;A0529;FT-0633997;EN300-19720;D88274;J-013333;Q27260326

Chemical Property of 2-Aminophenylarsonic acid

Chemical Property:

• Appearance/Colour: Gray-beige crystalline powder.
• Vapor Pressure: 1.31E-11mmHg at 25°C
• Melting Point: 145-150 ºC
• Boiling Point: 519.3 °C at 760 mmHg
• PKA: pK1: ca 2;pK2: 3.77;pK3: 8.66 (25°C)
• Flash Point: 267.8 °C
• PSA: 83.55000
• Density: g/cm³
• LogP: -0.58900
• Solubility.: 1 M NH4OH: soluble50mg/mL, clear to turbid (orange-brown)
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 216.972013
• Heavy Atom Count: 11
• Complexity: 179

Purity/Quality:

98% ^*data from raw suppliers

2-ArsanilicAcid ^*data from reagent suppliers

Safty Information:

• Hazard Codes: T,N
• Statements: 23/25-50/53
• Safety Statements: 20/21-28-45-60-61-28A

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)N)[As](=O)(O)O
• Uses: o-Arsanilic Acid is an organoarsenic compound. o-Arsanilic Acid is a highly toxic contaminant and can be found in plants growing in contaminated soil.

Technology Process of 2-Aminophenylarsonic acid

There total 17 articles about 2-Aminophenylarsonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-nitrophenylarsonic acid (5410-29-7) → o-arsanilic acid (2045-00-3)

Guidance literature:

With iron(II) chloride; in kalter alkalischer Loesung;

Reference yield:

2-Nitrophenyldiazonium (25910-37-6) → o-arsanilic acid (2045-00-3)

Guidance literature:

Multi-step reaction with 2 steps

1: alkali; sodium arsenite

2: NaOH-solution; ferrosulfate

With sodium hydroxide; trisodium arsenite; iron(II) sulfate;

Reference yield:

o-chlorophenylarsonic acid (33781-24-7) → o-arsanilic acid (2045-00-3) + (2,2'-imino-diphenyl)-bis-arsonic acid

Guidance literature:

With pentan-1-ol; copper diacetate; potassium carbonate; at 135 ℃;

DOI:10.1021/ja01359a035

upstream raw materials:

2-nitrophenylarsonic acid

sodium acetate

N,N'-bis-(2-arsono-phenyl)-oxalamide

o-chlorophenylarsonic acid

Downstream raw materials:

(2-p-toluidino-phenyl)-arsonic acid

2-iodophenylamine

N-(2-arsono-phenyl)-anthranilic acid

(2-benzylidenamino-phenyl)-arsonic acid

Refernces

• 1、 -. "Asymmetric dioxazine compounds and method for dyeing or printing fiber materials using the same". . . Retrieved 2008/06/13.
• 2、 -. "Asymmetric dioxazine compounds having a triazinyl bridging group and a method of production and use thereof". . . Retrieved 2008/06/13.