(3-Benzylphenyl)MethanaMine

Base Information

• Chemical Name: (3-Benzylphenyl)MethanaMine
• CAS No.: 74672-16-5
• Molecular Formula: C14H15N
• Molecular Weight: 197.28
• Mol file: 74672-16-5.mol

Synonyms:(3-Benzylphenyl)MethanaMine

Chemical Property of (3-Benzylphenyl)MethanaMine

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (3-Benzylphenyl)MethanaMine

There total 5 articles about (3-Benzylphenyl)MethanaMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

3-Benzylbenzyl alcohol (35714-19-3) → [3-((phenylmethyl)phenyl)methyl]amine (74672-16-5)

Guidance literature:

With sodium azide; triphenylphosphine; In dichloromethane; N,N-dimethyl-formamide; at 90 ℃; for 5h;

DOI:10.1080/00397910008087402

Reference yield: 85.5%

3-benzoylbenzonitrile (6136-62-5) → [3-((phenylmethyl)phenyl)methyl]amine (74672-16-5)

Guidance literature:

With potassium hydroxide; Raney Ni-Al alloy; In water; at 90 ℃; for 9h;

DOI:10.1080/00397910801929762

Reference yield: 27.0%

3-benzylbenzonitrile (93717-55-6) → [3-((phenylmethyl)phenyl)methyl]amine (74672-16-5)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; for 4h; Heating;

DOI:10.1021/jm070715d

upstream raw materials:

3-Benzylbenzyl alcohol

3-benzylbenzonitrile

3-benzoylbenzonitrile

Refernces

• 1、 Xue, Zhi Zhao,Semenova, Elena A.,Vu, B. Christie,Maddali, Kasthuraiah,Marchand, Christophe,Hughes, Stephen H.,Pommier, Yves,Burke Jr., Terrence R.. "2,3-Dihydro-6,7-dihydroxy-1H-isoindol-1-one-based HIV-1 integrase inhibitors". . p. 251 - 259. Retrieved 2008/09/19.
• 2、 -. "Heterocyclic compounds, pharmaceutical compositions comprising same, and methods for inhibiting β-amyloid peptide release and/or its synthesis by use of such compounds". . . Retrieved 2008/06/13.