2,2-Dibromo-1-methylcyclopropanecarbonitrile

Base Information

• Chemical Name: 2,2-Dibromo-1-methylcyclopropanecarbonitrile
• CAS No.: 63262-97-5
• Molecular Formula: C5H5Br2N
• Molecular Weight: 238.91
• Hs Code.: 2926909090
• Mol file: 63262-97-5.mol

Synonyms:2,2-Dibromo-1-methylcyclopropanecarbonitrile

Chemical Property of 2,2-Dibromo-1-methylcyclopropanecarbonitrile

Chemical Property:

• Melting Point: 30-32 °C
• Boiling Point: 252.1±40.0 °C(Predicted)
• PSA: 23.79000
• Density: 2.09±0.1 g/cm3(Predicted)
• LogP: 2.40608

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,2-Dibromo-1-methylcyclopropanecarbonitrile

There total 3 articles about 2,2-Dibromo-1-methylcyclopropanecarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.3%

Bromoform (75-25-2) + methacrylonitrile (126-98-7,25067-61-2) → 2,2-dibromo-1-methylcyclopropanecarbonitrile (63262-97-5)

Guidance literature:

With benzyltriethylammonium bromide; sodium hydroxide; at 20 ℃; for 4h;

Reference yield:

bromodiiodomethane (557-95-9) + methacrylonitrile (126-98-7,25067-61-2) → 2,2-dibromo-1-methylcyclopropanecarbonitrile (63262-97-5) + 2-Brom-2-iod-1-methyl-1-cyclopropancarbonitril (84060-84-4,84060-86-6) + 2,2-Diiod-1-methyl-1-cyclopropancarbonitril (84060-85-5)

Guidance literature:

With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In dichloromethane; for 17h; Yield given. Yields of byproduct given; Ambient temperature;

Reference yield:

dibromoiodomethane (593-94-2) + methacrylonitrile (126-98-7,25067-61-2) → 2,2-dibromo-1-methylcyclopropanecarbonitrile (63262-97-5) + 2-Brom-2-iod-1-methyl-1-cyclopropancarbonitril (84060-84-4,84060-86-6) + 2,2-Diiod-1-methyl-1-cyclopropancarbonitril (84060-85-5)

Guidance literature:

With sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride; In dichloromethane; for 17h; Yield given. Yields of byproduct given; Ambient temperature;

upstream raw materials:

Bromoform

methacrylonitrile

bromodiiodomethane

dibromoiodomethane

Downstream raw materials:

1-Methylcyclopropancarbonsaeurenitril

2,2-bis(phenylthio)-1-methylcyclopropanecarbonitrile

Refernces

• 1、 -. "A process for preparing 1-methyl propyl formic acid method". Paragraph 0036; 0037. . Retrieved 2017/02/09.
• 2、 Dehmlow, Eckehard V.,Broda, Witold. "Applications of Phase Transfer Catalysis, 23. Note on Bromoiodocarbene and on Pertinent Halogen Exchange Processes". . p. 3894 - 3897. Retrieved 2007/10/02.