benzo[g]isoquinoline

Base Information

• Chemical Name: benzo[g]isoquinoline
• CAS No.: 260-32-2
• Molecular Formula: C13H9 N
• Molecular Weight: 179.2173
• Mol file: 260-32-2.mol

Synonyms:2-Azaanthracene;b-Azaanthracene

Chemical Property of benzo[g]isoquinoline

Chemical Property:

• Vapor Pressure: 3.18E-05mmHg at 25°C
• Melting Point: 169-171 °C(Solv: methanol (67-56-1))
• Boiling Point: 366°Cat760mmHg
• PKA: 5.37±0.30(Predicted)
• Flash Point: 166.3°C
• PSA: 12.89000
• Density: 1.187g/cm³
• LogP: 3.38800

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of benzo[g]isoquinoline

There total 10 articles about benzo[g]isoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

4-Benzyl-pyridine-3-carbaldehyde (138823-83-3) → 2-azaanthracene (260-32-2)

Guidance literature:

With PPA; at 140 ℃; for 1h;

DOI:10.1002/jhet.5570350328

Reference yield: 60.0%

3-ethynyl-2-naphthaldehyde → 2-azaanthracene (260-32-2)

Guidance literature:

With ammonium acetate; silver nitrate; In acetonitrile; tert-butyl alcohol; at 22 ℃; Inert atmosphere;

DOI:10.1021/acs.orglett.0c04243

Reference yield: 43.0%

5,10-dihydro-5,10-epoxybenzisoquinoline (96913-99-4) → 2-azaanthracene (260-32-2)

Guidance literature:

With diiron nonacarbonyl; In benzene; for 6h; Heating;

DOI:10.1021/jo00215a031

upstream raw materials:

4-[(2-methylphenyl)methyl]pyridine

3-Methylpyridine

benzyl chloride

5,10-dihydro-5,10-epoxybenzisoquinoline

Downstream raw materials:

benzoisoquinolinium benzoylmethylid

benzoisoquinolinium dibenzoylmethylid

3-benzoyl-1,2-dicarbomethoxynaphth<2,3-g>indolizine

2-phenacylbenzoisoquinolinium bromide

Refernces

• 1、 Krapcho,Gilmor. "General synthetic route to benz[g]isoquinolines (2-azaanthracenes)". . p. 669 - 674. Retrieved 2007/10/03.
• 2、 Prostakov, N. S.,Kuznetsov, V. I.,Datta Rai, G.. "SUBSTITUTED 2- AND 4-BENZYLPYRIDINES IN THE SYNTHESIS OF BENZOQUINOLINES AND BENZOISOQUINOLINES". . p. 525 - 529. Retrieved 2007/10/02.