7-Deazadenosine

Base Information Edit

Chemical Name:7-Deazadenosine
CAS No.:69-33-0
Molecular Formula:C11H14 N4 O4
Molecular Weight:266.257
Hs Code.:29419090
NSC Number:56408
DSSTox Substance ID:DTXSID60861614
Wikidata:Q105026690
Mol file:69-33-0.mol

Synonyms:7-Deazadenosine;NSC56408;2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol;4-Amino-7.beta.-D-ribofuranosyl-7H-pyrrolo(2,3-d)pyrimidine;7.beta.-D-Ribofuranosyl-7H-pyrrolo(2,3-d)pyrimidine-4-amine;(2R,3R,4S,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol;NSC-56408;TBC;7-pentofuranosyl-7h-pyrrolo[2,3-d]pyrimidin-4-amine;7H-Pyrrolo[2,3-d]pyrimidin-4-amine, 7-.beta.-D-ribofuranosyl-;SCHEMBL1652797;SCHEMBL20418952;SCHEMBL23982115;DTXSID60861614;(2R,3R,4R,5R)-2-(4-aminopyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)oxolane-3,4-diol;HDZZVAMISRMYHH-UHFFFAOYSA-N;7H-Pyrrolo(2, 4-amino-7.beta.-D-ribofuranosyl-;WLN: T56 BN GN INJ FZ I- BT5OTJ CQ DQ E1Q;4-Amino-7-(.beta.-D-ribofuranosyl)-pyrrolo(2,3-d)pyrimidine;4-Amino-7-.beta.-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine;7-.beta.-D-ribofuranosyl-7H-pyrrolo-[2,3-d]pyrimidin-4-amine;7H-Pyrrolo(2,3-d)pyrimidine, 4-amino-7.beta.-D-ribofuranosyl-;(2R,3R,4S,5R)-2-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-(hydroxymethyl)-tetrahydrofuran-3,4-diol

Suppliers and Price of 7-Deazadenosine

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Usbiological
7-Deazaadenosine
10mg
$ 355.00

TRC
TubercidinTrifluoroacetate
100mg
$ 970.00

Sigma-Aldrich
Tubercidin from
250mg
$ 2060.00

Sigma-Aldrich
Tubercidin from
10mg
$ 185.00

Sigma-Aldrich
Tubercidin from
50mg
$ 687.00

Medical Isotopes, Inc.
7-Deazaadenosine 98%purewithdatedHPLCUVchromatogram
1 mg
$ 655.00

Medical Isotopes, Inc.
7-Deazaadenosine 98%purewithdatedHPLCUVchromatogram
5 mg
$ 935.00

DC Chemicals
Tubercidin >98%
1 g
$ 1100.00

DC Chemicals
Tubercidin >98%
250 mg
$ 500.00

DC Chemicals
Tubercidin >98%
100 mg
$ 300.00

Total 57 raw suppliers

Chemical Property of 7-Deazadenosine Edit

Chemical Property:

Vapor Pressure:1.02E-17mmHg at 25°C
Melting Point:247-248 °C (decomp)(Solv: water (7732-18-5))
Refractive Index:1.8340 (estimate)
Boiling Point:648.8 °C at 760 mmHg
PKA:12.44±0.70(Predicted)
Flash Point:346.2 °C
PSA：126.65000
Density:1.9 g/cm³
LogP:-0.79380
Storage Temp.:Keep in dark place,Inert atmosphere,Room temperature
Solubility.:Soluble in DMSO
XLogP3:-1.3
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:2
Exact Mass:266.10150494
Heavy Atom Count:19
Complexity:334

Purity/Quality:

98%min ^*data from raw suppliers

7-Deazaadenosine ^*data from reagent suppliers

Safty Information:

Pictogram(s): T+
Hazard Codes:T+
Statements: 28
Safety Statements: 36/37/39-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CN(C2=NC=NC(=C21)N)C3C(C(C(O3)CO)O)O
Recent EU Clinical Trials:A phase 1/2a, first-in-human, open-label, multicenter, dose escalation study of MP0533 in patients with relapsed/refractory (R/R) acute myeloid leukemia (AML) or myelodysplastic syndrome (MDS)
Uses Tubercidin is a nucleoside metabolite first isolated from Streptomyces tubericidus. Tubercidin, like other nucleosides, is a broad spectrum, potent chemotherapeutic agent active against viruses, bacteria, fungi, protozoans and tumours. Tubercidin acts at a diverse range of sites, such as RNA processing, nucleic acid and protein synthesis, and acts as a nucleoside mimic of adenosine.

Technology Process of 7-Deazadenosine

There total 20 articles about 7-Deazadenosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%