Adenylyl-(3'-5')-uridine

Base Information

• Chemical Name: Adenylyl-(3'-5')-uridine
• CAS No.: 3051-84-1
• Molecular Formula: C19H24 N7 O12 P
• Molecular Weight: 573.413
• European Community (EC) Number: 221-268-7
• NSC Number: 92172
• Mol file: 3051-84-1.mol

Synonyms:adenylyl-(3'-5')-uridine

Chemical Property of Adenylyl-(3'-5')-uridine

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 2.23g/cm³
• XLogP3: -5.4
• Hydrogen Bond Donor Count: 7
• Hydrogen Bond Acceptor Count: 16
• Rotatable Bond Count: 8
• Exact Mass: 573.12205622
• Heavy Atom Count: 39
• Complexity: 1030

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CN(C(=O)NC1=O)C2C(C(C(O2)COP(=O)(O)OC3C(OC(C3O)N4C=NC5=C(N=CN=C54)N)CO)O)O

Technology Process of Adenylyl-(3'-5')-uridine

There total 23 articles about Adenylyl-(3'-5')-uridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

2',3'-O-bis-di-n-propylphosphinothioyluridylyl-(5'-3')-adenosine → phosphoric acid adenosin-3'-yl ester uridin-5'-yl ester (3051-84-1)

Guidance literature:

With ammonia;

Reference yield: 52.0%

2',3'-O-bis-di-n-butylphosphinothioyluridylyl-(5'-3')-adenosine (125444-61-3) → phosphoric acid adenosin-3'-yl ester uridin-5'-yl ester (3051-84-1)

Guidance literature:

With ammonia;

Reference yield: 50.0%

2',3'-O-bis-diethylphosphinothioyluridylyl-(5'-3')-adenosine (125444-59-9) → phosphoric acid adenosin-3'-yl ester uridin-5'-yl ester (3051-84-1)

Guidance literature:

With ammonia; for 48h; Ambient temperature;

upstream raw materials:

2',3'-O-Isopropylideneuridylyl(5'-3')-adenosine

A(NBzl)-U

2',3'-O-Bis-diphenylphosphinothioyluridylyl(5'-3')-adenosine

C₇₅H₆₅ClN₇O₁₈P

Downstream raw materials:

adenosine monophosphate

adenosine 2'-monophosphate

adenosine 2',3'-cyclic monophosphate

uridine

Refernces

• 1、 Saneyoshi, Hisao,Ando, Kaori,Seio, Kohji,Sekine, Mitsuo. "Chemical synthesis of RNA via 2′-O-cyanoethylated intermediates". . p. 11195 - 11203. Retrieved 2008/03/11.
• 2、 Foeldesi, Andras,Nilson, Frans Peder R.,Glemarec, Corine,Gioeli, Carlo,Chattopadhyaya, Jyoti. "Synthesis of 1'%,2',3',4'%,5',5"-(2)H6-β-D-ribonucleosides and 1'%,2',2",3',4'%,5',5"-(2)H7-β-D-2'-deoxyribonucleosides for Selective Suppression of Proton Resonances in Partially-deuterated Oligo-DNA, Oligo-RNA and in 2,5A core ((1)H-NMR window)". . p. 9033 - 9072. Retrieved 2007/10/02.