Oxytetracycline dihydrate

Base Information

• Chemical Name: Oxytetracycline dihydrate
• CAS No.: 6153-64-6
• Molecular Formula: C22H24N2O9^.2(H2O)
• Molecular Weight: 496.471
• Hs Code.: 29413000
• Mol file: 6153-64-6.mol

Synonyms:2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-,dihydrate (8CI);2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-,dihydrate, [4S-(4a,4aa,5a,5aa,6b,12aa)]-;5-Hydroxytetracycline dihydrate;2-Naphthacenecarboxamide,4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-,hydrate (1:2), (4S,4aR,5S,5aR,6S,12aS)-;

Chemical Property of Oxytetracycline dihydrate

Chemical Property:

• Appearance/Colour: Yellow crystalline powder
• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 181-182 °C
• Boiling Point: 951.8 °C at 760 mmHg
• Flash Point: 529.4 °C
• PSA: 220.31000
• LogP: -0.67190
• Storage Temp.: 0-6°C
• Solubility.: 1 M HCl: 0.1 M yellow to yellow-orange, clear
• Water Solubility.: slightly soluble

Purity/Quality:

99% ^*data from raw suppliers

Oxytetracycline dihydrate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,Xi
• Hazard Codes: Xn,Xi
• Statements: 63-36-36/37/38
• Safety Statements: 22-24/25-36/37/39-26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Description: Oxytetracycline is an important member of the bacterial aromatic polyketide family, which is a structurally diverse class of natural products. It's a prescription antibiotic that interferes with bacteria's ability to produce essential proteins.
• Uses: Antibiotic substance isolated from the elaboration products of the actinomycete, Streptomyces rimosus, grown on a suitable medium. Antibacterial. antihypertensive

Technology Process of Oxytetracycline dihydrate

There total 2 articles about Oxytetracycline dihydrate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

oxytetracycline hydrochloride acetate → oxytetracycline hydrate (6153-64-6)

Guidance literature:

With concentrated ammonia; In water;

Reference yield:

→ (4S,4aR,5S,6S,12aS)-4-Dimethylamino-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydro-naphthacene-2-carboxylic acid amide (79-57-2,14206-58-7,22042-27-9,35259-39-3,65309-81-1,6153-64-6)

Guidance literature:

Isolierung durch Ionenaustauschchromatographie;

Refernces