2-amino-3-chloro-N-hydroxypropanamide

Base Information

• Chemical Name: 2-amino-3-chloro-N-hydroxypropanamide
• CAS No.: 120854-55-9
• Molecular Formula: C3H7ClN2O2
• Molecular Weight: 138.554
• Mol file: 120854-55-9.mol

Synonyms:2-amino-3-chloro-N-hydroxypropanamide;2-AMino-3-chloro-propionohydroxaMic

Chemical Property of 2-amino-3-chloro-N-hydroxypropanamide

Chemical Property:

• PSA: 78.84000
• LogP: 0.59850
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly, Heated), Water (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

2-Amino-3-chloro-N-hydroxy-propanamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Intermediate in the preparation of Cycloserine (C988800).

Technology Process of 2-amino-3-chloro-N-hydroxypropanamide

There total 2 articles about 2-amino-3-chloro-N-hydroxypropanamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

DL-2,5-Dioxo-4-chlormethyloxazolidin (3981-41-7,96165-57-0) → 3-chloro-DL-alanine hydroxyamide (120854-55-9)

Guidance literature:

With hydrogenchloride; ethanol; water; hydroxylamine; triethylamine;

DOI:10.1002/hlca.19570400536

Reference yield:

→ 3-chloro-DL-alanine hydroxyamide (120854-55-9)

Guidance literature:

With hydrogenchloride; chloroform; benzene;

Reference yield:

3-chloro-DL-alanine hydroxyamide (120854-55-9) → 4-amino-3-isoxazolidone (68-39-3,68-41-7,339-72-0,4834-58-6)

Guidance literature:

With triethylamine;

DOI:10.1002/hlca.19570400536

upstream raw materials:

DL-2,5-Dioxo-4-chlormethyloxazolidin

Downstream raw materials:

4-amino-3-isoxazolidone