MOC-D-Norleucine

Base Information

• Chemical Name: MOC-D-Norleucine
• CAS No.: 1261072-86-9
• Molecular Formula: C8H15NO4
• Molecular Weight: 189.21
• Mol file: 1261072-86-9.mol

Synonyms:MOC-D-Norleucine

Chemical Property of MOC-D-Norleucine

Chemical Property:

• Boiling Point: 336.1±25.0 °C(Predicted)
• PKA: 4.45±0.21(Predicted)
• PSA: 75.63000
• Density: 1.126±0.06 g/cm3(Predicted)
• LogP: 1.37670

Purity/Quality:

98%, 99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of MOC-D-Norleucine

There total 2 articles about MOC-D-Norleucine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

L-Norleucine (327-57-1) + methyl chloroformate (79-22-1) → C8H15NO4 (1261072-86-9,911481-41-9)

Guidance literature:

With sodium hydroxide; In water; at 20 ℃;

DOI:10.1111/cbdd.12438

Reference yield:

2-amino-hexanoic acid (616-06-8) + methyl chloroformate (79-22-1) → N-methoxycarbonyl-norleucine (1261072-86-9,911481-41-9)

Guidance literature:

With sodium hydroxide; sodium carbonate;

upstream raw materials:

2-amino-hexanoic acid

methyl chloroformate

L-Norleucine

Refernces

• 1、 Weng, Zhijie,Zheng, Yongyong,Li, Jianqi. "Synthesis, antidepressant activity, and toxicity of the erythro/threo racemates and optical isomers of 2-(4-benzylpiperazin-1-yl)-1-(5-chloro-6-methoxynaphthalen-2-yl)hexan-1-ol". . p. 454 - 460. Retrieved 2015/03/18.