3-aminopropyl(methyl)phosphinic Acid

Base Information

• Chemical Name: 3-aminopropyl(methyl)phosphinic Acid
• CAS No.: 127729-35-5
• Molecular Formula: C4H12 N O2 P
• Molecular Weight: 137.119
• European Community (EC) Number: 802-793-6
• DSSTox Substance ID: DTXSID80925969
• Nikkaji Number: J364.038H
• Wikipedia: SKF-97,541
• Wikidata: Q7390605
• ChEMBL ID: CHEMBL112710
• Mol file: 127729-35-5.mol

Synonyms:3-aminopropyl(methyl)phosphinic acid;3-APMPA;SK and F 97541;SKF-97541;SKF97541

Chemical Property of 3-aminopropyl(methyl)phosphinic Acid

Chemical Property:

• Appearance/Colour: solid
• Vapor Pressure: 1.13E-06mmHg at 25°C
• Boiling Point: 375.4 °C at 760 mmHg
• Flash Point: 180.9 °C
• PSA: 73.13000
• LogP: 1.73770
• Storage Temp.: Desiccate at RT
• Solubility.: H2O: soluble
• XLogP3: -4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 137.06056562
• Heavy Atom Count: 8
• Complexity: 104

Purity/Quality:

98%Min ^*data from raw suppliers

SKF 97541 ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CP(=O)(CCCN)O
• Uses: SKF-97541 acts as a highly potent agonist of GABAB receptors. Shown to display sedative effects in mammals and may be used in the treatment of various addictions due to neurochemical imbalances.

Technology Process of 3-aminopropyl(methyl)phosphinic Acid

There total 2 articles about 3-aminopropyl(methyl)phosphinic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-aminopropyl(methyl)phosphinic acid (127729-35-5)

Guidance literature:

Reference yield:

→ 3-aminopropyl(methyl)phosphinic acid (127729-35-5) + CGP 44530

Guidance literature:

Reference yield:

1-[[[(2,5-dioxopyrrolidin-1-yl)oxy]carbonyl]oxy]ethyl 2-methylpropanoate (860035-10-5) + 3-aminopropyl(methyl)phosphinic acid (127729-35-5) → 3-{[1-isobutanoyloxyethoxy]carbonylamino}propyl methylphosphinic acid

Guidance literature:

In acetonitrile; at 20 ℃; for 16h;

Refernces

• 1、 -. "Use of GABAB receptor agonists as reflux inhibitors". . . Retrieved 2008/06/13.