4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt

Base Information

• Chemical Name: 4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt
• CAS No.: 206443-06-3
• Molecular Formula: C16H17NaO11S
• Molecular Weight: 440.35435
• Hs Code.: 2932209090
• Mol file: 206443-06-3.mol

Synonyms:4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt;4-Methylumbelliferyl β-D-galactopyranoside-6-sulphate sodium salt;4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate Sodium Salt;4-Methyl-7-[(6-O-sulfo-β-D-galactopyranosyl)oxy]-;4-Methyl-7-[(6-O-sulfo-beta-D-galactopyranosyl)oxy]-2H-1-benzopyran-2-one monosodium salt

Chemical Property of 4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt

Chemical Property:

• Melting Point: 196-198?C
• PSA: 184.17000
• LogP: -0.15460
• Storage Temp.: -20°C Freezer, Under Inert Atmosphere
• Solubility.: Methanol (Slightly, Sonicated), Water (Slightly)

Purity/Quality:

98% ^*data from raw suppliers

4-Methylumbelliferyl b-D-galactopyranoside-6-sulphate sodium salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: 4-Methylumbelliferyl β-D-Galactopyranoside-6-sulfate (sodium salt) (4-MU-Gal-6S) is a fluorogenic substrate used to quantify N-acetylgalactosamine-6-sulphatase (GALNS) activity. 4-MU-Gal-6S is cleaved by GALNS to release the fluorescent moiety 4-MU. 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an emission maximum ranging from 445 to 455 nM, increasing as pH decreases. It has been used to detect Morquio disease type A, a lysosomal storage disorder in which GALNS is deficient. 4-MU-Gal-6S can be used to assess GALNS activity in a very small blood volume to determine the extent of deficiency.
• Uses: Used for the determination of galactose-6-sulphate sulphatase activity. Used in the diagnosis of Mucopolysaccharidosis IV A. 4-Methylumbelliferylb-D-galactopyranoside-6-sulphatesodiumsalt is used for the determination of galactose-6-sulphate sulphatase activity,it is used in the diagnosis of Mucopolysaccharidosis IV A.