Glycine, N,N'-(1R,2R)-1,2-cyclohexanediylbis[N-(carboxymethyl)-, rel-

Base Information

• Chemical Name: Glycine, N,N'-(1R,2R)-1,2-cyclohexanediylbis[N-(carboxymethyl)-, rel-
• CAS No.: 482-54-2
• Deprecated CAS: 21309-46-6,97138-58-4
• Molecular Formula: C14H22N2O8
• Molecular Weight: 346.337
• Hs Code.: 2922499990
• European Community (EC) Number: 236-308-9
• UNII: JD2BU42P20
• DSSTox Substance ID: DTXSID10889383
• Nikkaji Number: J89.945C
• Wikidata: Q27281446
• Mol file: 482-54-2.mol

Synonyms:13291-61-7;Glycine, N,N'-(1R,2R)-1,2-cyclohexanediylbis[N-(carboxymethyl)-, rel-;2,2',2'',2'''-((1R,2R)-rel-Cyclohexane-1,2-diylbis(azanetriyl))tetraacetic acid;trans-Cyclohexane-1,2-dinitrilotetraacetic acid;UNII-JD2BU42P20;JD2BU42P20;trans-1,2-Cyclohexanediaminetetraacetic Acid;EINECS 236-308-9;2-[[(1R,2R)-2-[bis(carboxymethyl)amino]cyclohexyl]-(carboxymethyl)amino]acetic acid;Glycine, N,N'-(1R,2R)-1,2-cyclohexanediylbis(N-(carboxymethyl)-, rel-;rel-2,2',2'',2'''-((1R,2R)-Cyclohexane-1,2-diylbis(azanetriyl))tetraacetic acid;Acetic acid, (1,2-cyclohexylenedinitrilo)tetra-, trans-;trans-1,2-Diaminocyclohexane-N,N,N',N'-tetraacetic acid;trans-cyclohexane-1,2-diamine-n,n,n',n'-tetraacetic acid;Glycine, N,N'-1,2-cyclohexanediylbis[N-(carboxymethyl)-, trans-;NSC-7339;Glycine, N,N'-1,2-cyclohexanediylbis(N-(carboxymethyl)-, trans-;C14-H22-N2-O8;NSC-529593;CHELATON 4;Cyclohexane-1,2-dinitrilotetraacetic acid, trans-;(CyDTA);SCHEMBL93743;Glicina, n,n'-(1r,2r)-1,2-ciclohexanodiilbis[n-(carboximetil)-, rel-;DTXSID10889383;Cyclohexanediaminetetoraacetic acid;FCKYPQBAHLOOJQ-NXEZZACHSA-N;AC-2121;FS-3809;HY-45290;PD157952;CS-0145636;Cyclohexane-1,2-diaminetetraacetic acid, trans;E79142;CYCLOHEXANEDIAMINE TETRAACETIC ACID [INCI];W-108304;Q27281446;CYCLOHEXANE-1,2-DIAMINE-N,N,N',N'-TETRAACETIC ACID, TRANS-;trans-1,2-Diaminocyclohexane-N,N,N',N'-tetracetic acid monohydrate;TRANS-(+/-)-N,N'-1,2-CYCLOHEXANEDIYLBIS(N-(CARBOXYMETHYL)GLYCINE);2,2',2'',2'''-((1R,2R)-Cyclohexane-1,2-diylbis(azanetriyl))tetraacetic acid;2,2',2'',2'''-(1R, 2R)-rel-(Cyclohexane-1,2-diylbis(azanetriyl))tetraacetic acid hydrate

Chemical Property of Glycine, N,N'-(1R,2R)-1,2-cyclohexanediylbis[N-(carboxymethyl)-, rel-

Chemical Property:

• Vapor Pressure: 1.9E-18mmHg at 25°C
• Boiling Point: 670.8 °C at 760 mmHg
• Flash Point: 359.487 °C
• PSA: 164.91000
• Density: 1.489 g/cm³
• LogP: -0.82430
• XLogP3: -4.5
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 10
• Exact Mass: 346.13761566
• Heavy Atom Count: 24
• Complexity: 419

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Other Uses -> Chelating Agents
• Canonical SMILES: C1CCC(C(C1)N(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O
• Isomeric SMILES: C1CC[C@H]([C@@H](C1)N(CC(=O)O)CC(=O)O)N(CC(=O)O)CC(=O)O

Technology Process of Glycine, N,N'-(1R,2R)-1,2-cyclohexanediylbis[N-(carboxymethyl)-, rel-

There total 3 articles about Glycine, N,N'-(1R,2R)-1,2-cyclohexanediylbis[N-(carboxymethyl)-, rel- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

rac-diaminocyclohexane (694-83-7) + chloroacetic acid (79-11-8) → Cyclohexan-1.2-diamin-N.N.N'.N'-tetraessigsaeure (482-54-2)

Guidance literature:

rac-diaminocyclohexane; chloroacetic acid; With tetramethyl ammoniumhydroxide; In water; at 100 ℃; for 1h;

With hydrogenchloride; In water; pH=2;

Reference yield:

→ Cyclohexan-1.2-diamin-N.N.N'.N'-tetraessigsaeure (482-54-2)

Guidance literature:

1,2-Diaminocyclohexansulfat, ClCH2COOH;

Reference yield:

→ (R,R)-trans-1,2-cyclohexanediaminetetraacetic acid (482-54-2,13291-61-7,28684-63-1,92761-25-6,97138-58-4)

Guidance literature:

upstream raw materials:

rac-diaminocyclohexane

chloroacetic acid

Downstream raw materials:

Eu⁽³⁺⁾*((OOCCH₂)2N)2C₆H₁₀^(4-)=Eu(((OOCCH₂)2N)2C₆H₁₀)^(1-)

Eu⁽³⁺⁾*((OOCCH₂)2N)2C₆H₁₀^(4-)*(OOCCH₂)2NH^(2-)=Eu((OOCCH₂)2NH)(((OOCCH₂)2N)2C₆H₁₀)^(3-)

1,2-cyclohexanediaminetetraacetic acid ammonium salt

Refernces

• 1、 -. "Preparation and purification of hydroxylamine stabilizers". Page/Page column 3. . Retrieved 2008/06/13.
• 2、 -. "Methods for controlling intraocular pressure with transition metal complexes". . . Retrieved 2008/06/13.