N,N-Bis(4-bromophenyl)-4-fluoroaniline

Base Information

• Chemical Name: N,N-Bis(4-bromophenyl)-4-fluoroaniline
• CAS No.: 1429194-04-6
• Molecular Formula: C₁₈H₁₂Br₂FN
• Molecular Weight: 421.106
• European Community (EC) Number: 833-583-2
• Mol file: 1429194-04-6.mol

Synonyms:N,N-Bis(4-bromophenyl)-4-fluoroaniline;1429194-04-6;MFCD31618116;C18H12Br2FN;SCHEMBL18381153;4,4'-Dibromo-4''-fluorotriphenylamine;BS-44636;SY234415;N,N-Bis(4-bromophenyl)-4-fluorobenzenamine;B5637;T70278

Chemical Property of N,N-Bis(4-bromophenyl)-4-fluoroaniline

Chemical Property:

• XLogP3: 6.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 420.93000
• Heavy Atom Count: 22
• Complexity: 308

Purity/Quality:

98% GC ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1=CC(=CC=C1N(C2=CC=C(C=C2)Br)C3=CC=C(C=C3)Br)F

Technology Process of N,N-Bis(4-bromophenyl)-4-fluoroaniline

There total 4 articles about N,N-Bis(4-bromophenyl)-4-fluoroaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-bromo-N-(4-bromophenyl)-N-(4-nitrophenyl)amine (144393-34-0) → 4-fluoro-4',4''-dibromotriphenylamine (1429194-04-6) + 3,4',4''-tribromotriphenylamine

Guidance literature:

4-bromo-N-(4-bromophenyl)-N-(4-nitrophenyl)amine; With tin; acetic acid; at 75 ℃; for 1h;

With tetrafluoroboric acid; sodium nitrite; In water; at 0 - 20 ℃; for 25h;

at 200 ℃;

DOI:10.1021/ol0603458

Reference yield:

N,N-diphenylaminobenzene (603-34-9) → 4-fluoro-4',4''-dibromotriphenylamine (1429194-04-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: 41 percent / copper(II) nitrate; acetyc anhydride / 2 h / 20 °C

2.1: 99 percent / Br₂ / CH₂Cl₂ / 36 h

3.1: tin; acetic acid / 1 h / 75 °C

3.2: aq. NaNO₂; aq. HBF₄ / 0 - 20 °C

3.3: 200 °C

With tin; bromine; acetic anhydride; copper(II) nitrate; acetic acid; In dichloromethane;

DOI:10.1021/ol052558n

Reference yield:

4-nitrophenyldiphenylamine (4316-57-8) → 4-fluoro-4',4''-dibromotriphenylamine (1429194-04-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: 99 percent / Br₂ / CH₂Cl₂ / 36 h

2.1: tin; acetic acid / 1 h / 75 °C

2.2: aq. NaNO₂; aq. HBF₄ / 0 - 20 °C

2.3: 200 °C

With tin; bromine; acetic acid; In dichloromethane;

DOI:10.1021/ol052558n

upstream raw materials:

4-bromo-N-(4-bromophenyl)-N-(4-nitrophenyl)amine

N,N-diphenylaminobenzene

4-nitrophenyldiphenylamine

Refernces

• 1、 Mayers, Brian T.,Fry, Albert J.. "Construction of electrocatalytic electrodes bearing the triphenylamine nucleus covalently bound to carbon. A halogen dance in protonated aminotriphenylamines". . p. 411 - 414. Retrieved 2007/10/03.