(2S)-2-methylpiperidin-4-one hydrochloride

Base Information

• Chemical Name: (2S)-2-methylpiperidin-4-one hydrochloride
• CAS No.: 790667-45-7
• Molecular Formula: C6H12ClNO
• Molecular Weight: 149.62
• Hs Code.: 2933399090
• Mol file: 790667-45-7.mol

Synonyms:(2S)-2-methylpiperidin-4-one hydrochloride;4-Piperidinone, 2-methyl-, hydrochloride, (2S)-;2-(S)-Methyl-4-piperidinone hydrochloride

Chemical Property of (2S)-2-methylpiperidin-4-one hydrochloride

Chemical Property:

• PSA: 29.10000
• LogP: 1.45820
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C

Purity/Quality:

99.3% ^*data from raw suppliers

(2S)-2-methylpiperidin-4-onehydrochloride ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: (2S)-2-methylpiperidin-4-one hydrochloride is a useful research chemical.

Technology Process of (2S)-2-methylpiperidin-4-one hydrochloride

There total 1 articles about (2S)-2-methylpiperidin-4-one hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(S)-2-methylpiperidin-4-one acetic acid salt (790667-48-0) → (S)-2-methylpiperidin-4-one hydrochloride (790667-45-7,13729-77-6,1434126-97-2)

Guidance literature:

With hydrogenchloride; In water; isopropyl alcohol; toluene;

Reference yield: 95.0%

(S)-2-methylpiperidin-4-one hydrochloride (790667-45-7,13729-77-6,1434126-97-2) + di-tert-butyl dicarbonate (24424-99-5) → (S)-2-methyl-4-oxopiperidine-1-carboxylic acid tert-butyl ester (790667-49-1)

Guidance literature:

With sodium hydrogencarbonate; In dichloromethane; water; at 20 ℃;

Reference yield: 85.0%

(S)-2-methylpiperidin-4-one hydrochloride (790667-45-7,13729-77-6,1434126-97-2) + 4’-chloro-2-iodomethyl-biphenyl (1274804-87-3) → (S)-1-(4'-chloro-biphenyl-2-ylmethyl)-2-methyl-piperidin-4-one (1274804-93-1)

Guidance literature:

(S)-2-methylpiperidin-4-one hydrochloride; With potassium carbonate; In acetonitrile; for 0.25h;

4’-chloro-2-iodomethyl-biphenyl; In acetonitrile; at 70 ℃; for 16h;

upstream raw materials:

(S)-2-methylpiperidin-4-one acetic acid salt

Downstream raw materials:

(S)-2-methyl-4-oxopiperidine-1-carboxylic acid tert-butyl ester

(S)-1-(4'-chloro-biphenyl-2-ylmethyl)-2-methyl-piperidin-4-one

Refernces