5,10,15,20-Tetraphenyl-2,3-dihydroporphyrin

Base Information

• Chemical Name: 5,10,15,20-Tetraphenyl-2,3-dihydroporphyrin
• CAS No.: 2669-65-0
• Molecular Formula: C44H32N4
• Molecular Weight: 616.765
• DSSTox Substance ID: DTXSID20572178
• Nikkaji Number: J497.488C,J2.449.008D
• Mol file: 2669-65-0.mol

Synonyms:5,10,15,20-Tetraphenyl-2,3-dihydroporphyrin;5,10,15,20-tetraphenyl-2,3,22,24-tetrahydroporphyrin;SCHEMBL4413776;DTXSID20572178

Chemical Property of 5,10,15,20-Tetraphenyl-2,3-dihydroporphyrin

Chemical Property:

• Melting Point: >250℃
• PSA: 52.54000
• LogP: 8.97470
• Storage Temp.: Amber Vial, -20°C Freezer, Under inert atmosphere
• Solubility.: Chloroform (Slightly), Ethyl Acetate (Slightly, Sonicated)
• XLogP3: 10.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 616.26269704
• Heavy Atom Count: 48
• Complexity: 929

Purity/Quality:

98%,99%, ^*data from raw suppliers

meso-Tetraphenylchlorin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: C1CC2=NC1=C(C3=CC=C(N3)C(=C4C=CC(=N4)C(=C5C=CC(=C2C6=CC=CC=C6)N5)C7=CC=CC=C7)C8=CC=CC=C8)C9=CC=CC=C9
• Uses: meso-Tetraphenylchlorin (CAS# 2669-65-0) is a chlorin derivative which is able to absorb near-UV light. As a building block, meso-tetraphenylchlorinable to undergo regioselective reduction. Its use for drug-delivery via chemo-photodynamic therapy has also been explored.

Technology Process of 5,10,15,20-Tetraphenyl-2,3-dihydroporphyrin

There total 4 articles about 5,10,15,20-Tetraphenyl-2,3-dihydroporphyrin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

pyrrole (109-97-7,30604-81-0) + benzaldehyde (100-52-7) → 5,15,10,20-tetraphenylporphyrin (917-23-7,20998-75-8) + meso-tetraphenylchlorin (2669-65-0)

Guidance literature:

DOI:10.1021/ja01265a096 DOI:10.1021/ja01136a002 DOI:10.1021/ja01846a065 DOI:10.1021/jo01191a002 DOI:10.1021/ja01215a046

Reference yield:

→ meso-tetraphenylchlorin (2669-65-0)

Guidance literature:

With sodium; hexan-1-ol;

DOI:10.1021/ja01215a046

Reference yield:

5,15,10,20-tetraphenylporphyrin (917-23-7,20998-75-8) → meso-tetraphenylchlorin (2669-65-0)

Guidance literature:

With 1,4-dioxane; Pd-BaSO₄; Hydrogenation;

DOI:10.1021/ja01215a046

upstream raw materials:

pyrrole

benzaldehyde

5,15,10,20-tetraphenylporphyrin

Downstream raw materials:

tetraphenylisobacteriochlorin

Refernces