Acetylsalicylamide

Base Information Edit

Chemical Name:Acetylsalicylamide
CAS No.:5663-71-8
Molecular Formula:C9H9 N O3
Molecular Weight:179.175
Hs Code.:
European Community (EC) Number:227-120-8
UNII:496N9P3MZS
DSSTox Substance ID:DTXSID9046108
Nikkaji Number:J54.304G
Wikidata:Q27259233
Mol file:5663-71-8.mol

Synonyms:Acetylsalicylamide;2-carbamoylphenyl acetate;5663-71-8;o-acetylsalicylamide;Influina;(2-carbamoylphenyl) acetate;2-(Aminocarbonyl)phenyl acetate;O-Acetyl salicylamide;Benzamide, 2-(acetyloxy)-;Salicylamide, O-acetyl-;Salicylamide, acetate (ester);EINECS 227-120-8;BRN 2692708;UNII-496N9P3MZS;496N9P3MZS;4-10-00-00183 (Beilstein Handbook Reference);2-Acetoxybenzamide;2-carbamoylphenylacetate;Oprea1_431591;SCHEMBL811872;SCHEMBL10865315;2-(Aminocarbonyl)phenyl acetate #;AKOS003593720;LS-144135;ACETIC ACID 2-CARBAMOYL-PHENYL ESTER;Q27259233

Suppliers and Price of Acetylsalicylamide

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of Acetylsalicylamide Edit

Chemical Property:

Vapor Pressure:0.000262mmHg at 25°C
Melting Point:138 °C
Boiling Point:323.4°Cat760mmHg
PKA:15.48±0.50(Predicted)
Flash Point:171.8°C
PSA：70.38000
Density:1.229g/cm³
LogP:1.59500
XLogP3:0.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:179.058243149
Heavy Atom Count:13
Complexity:215

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OC1=CC=CC=C1C(=O)N

Technology Process of Acetylsalicylamide

There total 9 articles about Acetylsalicylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 108-24-7
acetic anhydride

: 65-45-2
salicylamide

: 5663-71-8
O-acetylsalicylamide

Guidance literature:: With pyridine; at 20 ℃;

Reference yield: 72.0%

: 75-36-5
acetyl chloride

: 65-45-2
salicylamide

: 5663-71-8
O-acetylsalicylamide

Guidance literature:: In benzene; for 0.166667h; Heating;

Reference yield: 56.0%

: 50-78-2,98201-60-6
aspirin

: 5663-71-8
O-acetylsalicylamide

Guidance literature:: aspirin; With chloroformic acid ethyl ester; triethylamine; In tetrahydrofuran; at 0 ℃; for 0.5h;

With ammonium chloride; In tetrahydrofuran; water; at 0 ℃; for 0.5h;
DOI:10.1016/j.tetasy.2017.10.015