1-(2,4-Dihydroxy-3-propylphenyl)-2,2,2-trifluoroethanone

Base Information Edit

Chemical Name:1-(2,4-Dihydroxy-3-propylphenyl)-2,2,2-trifluoroethanone
CAS No.:65239-69-2
Molecular Formula:C11H11F3O3
Molecular Weight:248.202
Hs Code.:
DSSTox Substance ID:DTXSID90561256
Mol file:65239-69-2.mol

Synonyms:1-(2,4-dihydroxy-3-propylphenyl)-2,2,2-trifluoroethanone;65239-69-2;2,4-dihydroxy-3-propyl-1',1',1'-trifluoroacetophenone;SCHEMBL13924190;DTXSID90561256;FNUWZRSFCFUFFU-UHFFFAOYSA-N;AKOS015969623;A835037;1-(2,4-Dihydroxy-3-propylphenyl)-2,2,2-trifluoroethan-1-one;1-[2,4-bis(oxidanyl)-3-propyl-phenyl]-2,2,2-tris(fluoranyl)ethanone

Suppliers and Price of 1-(2,4-Dihydroxy-3-propylphenyl)-2,2,2-trifluoroethanone

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of 1-(2,4-Dihydroxy-3-propylphenyl)-2,2,2-trifluoroethanone Edit

Chemical Property:

XLogP3:3.9
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:248.06602869
Heavy Atom Count:17
Complexity:278

Purity/Quality:: 99%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCC1=C(C=CC(=C1O)C(=O)C(F)(F)F)O

Technology Process of 1-(2,4-Dihydroxy-3-propylphenyl)-2,2,2-trifluoroethanone

There total 8 articles about 1-(2,4-Dihydroxy-3-propylphenyl)-2,2,2-trifluoroethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 709028-25-1
1-(3-allyl-2,4-dihydroxy-phenyl)-2,2,2-trifluoro-ethanone

: 65239-69-2
2,4-dihydroxy-3-propyl-1',1',1'-trifluoroacetophenone

Guidance literature:: With hydrogen; palladium on activated charcoal; In various solvent(s); under 760 Torr;
DOI:10.1016/S0960-894X(03)00115-X

Reference yield:

: 13331-19-6
2-propyl-1,3-benzenediol

: 407-25-0
trifluoroacetic anhydride

: 65239-69-2
2,4-dihydroxy-3-propyl-1',1',1'-trifluoroacetophenone

Guidance literature:: With aluminium trichloride; In dichloromethane;
DOI:10.1016/S0960-894X(03)00702-9

Reference yield:

: 315-44-6
2,4-dihydroxy-1’,1’,1’-trifluoroacetophenone

: 65239-69-2
2,4-dihydroxy-3-propyl-1',1',1'-trifluoroacetophenone

Guidance literature:: Multi-step reaction with 3 steps

1: Cs₂CO₃ / dimethylformamide / 20 °C

2: 1,2-dichloro-benzene / Heating

3: 100 percent / H₂ / 5 percent Pd/C / various solvent(s) / 760 Torr

With hydrogen; caesium carbonate; palladium on activated charcoal; In N,N-dimethyl-formamide; 1,2-dichloro-benzene; 2: Claisen rearrangement;
DOI:10.1016/S0960-894X(03)00115-X