4-(2-Bromopropanoyl)-2-methoxyphenyl benzoate

Base Information

• Chemical Name: 4-(2-Bromopropanoyl)-2-methoxyphenyl benzoate
• CAS No.: 1774-09-0
• Molecular Formula: C₁₇H₁₅BrO₄
• Molecular Weight: 363.208
• NSC Number: 47104
• DSSTox Substance ID: DTXSID60286727
• Mol file: 1774-09-0.mol

Synonyms:1774-09-0;4-(2-bromopropanoyl)-2-methoxyphenyl benzoate;NSC47104;DTXSID60286727;NSC-47104

Chemical Property of 4-(2-Bromopropanoyl)-2-methoxyphenyl benzoate

Chemical Property:

• Vapor Pressure: 4.82E-10mmHg at 25°C
• Boiling Point: 497.7°Cat760mmHg
• Flash Point: 254.8°C
• Density: 1.405g/cm³
• XLogP3: 4.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 6
• Exact Mass: 362.01537
• Heavy Atom Count: 22
• Complexity: 392

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(=O)C1=CC(=C(C=C1)OC(=O)C2=CC=CC=C2)OC)Br

Technology Process of 4-(2-Bromopropanoyl)-2-methoxyphenyl benzoate

There total 1 articles about 4-(2-Bromopropanoyl)-2-methoxyphenyl benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(4-benzoyloxy-3-methoxy-phenyl)-propan-1-one (1911-49-5) → 1-(4-Benzoyloxy-3-methoxy-phenyl)-2-brom-1-propanon (1774-09-0)

Guidance literature:

With bromine; In chloroform;

Reference yield:

1-(4-Benzoyloxy-3-methoxy-phenyl)-2-brom-1-propanon (1774-09-0) → (1RS,2SR)-1-(3,4-dimethoxy-phenyl)-2-(2-methoxy-phenoxy)-propan-1-ol (1835-10-5,7107-92-8,36483-10-0)

Guidance literature:

Multi-step reaction with 3 steps

1: (i) K₂CO₃, KI, acetone, (ii) KOH, EtOH

2: NaBH₄, NaOH / methanol

3: diethyl ether

With sodium hydroxide; sodium tetrahydroborate; diethyl ether; In methanol;

Reference yield:

1-(4-Benzoyloxy-3-methoxy-phenyl)-2-brom-1-propanon (1774-09-0) → (1RS,2SR)-1-(4-hydroxy-3-methoxy-phenyl)-2-(2-methoxy-phenoxy)-propan-1-ol (1774-10-3,7107-90-6,7107-91-7,79999-55-6,80010-86-2)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) K₂CO₃, KI, acetone, (ii) KOH, EtOH

2: NaBH₄, NaOH / methanol

With sodium hydroxide; sodium tetrahydroborate; In methanol;

upstream raw materials:

1-(4-benzoyloxy-3-methoxy-phenyl)-propan-1-one

Downstream raw materials:

1-(4-hydroxy-3-methoxyphenyl)-2-(2-methoxyphenoxy)-1-propanone

2-Methoxy-4-<2-(2-methoxy-4-methyl)-phenoxypropionyl>-phenol

(1RS,2SR)-1-(4-hydroxy-3-methoxy-phenyl)-2-(2-methoxy-phenoxy)-propan-1-ol

(1RS,2SR)-1-(3,4-dimethoxy-phenyl)-2-(2-methoxy-phenoxy)-propan-1-ol