3-Methyl-4,6-dibromoaniline

Base Information

• Chemical Name: 3-Methyl-4,6-dibromoaniline
• CAS No.: 67643-51-0
• Molecular Formula: C7H7Br2N
• Molecular Weight: 264.947
• Hs Code.: 2921430090
• Mol file: 67643-51-0.mol

Synonyms:2,4-Dibromo-5-methylaniline;3-Methyl-4,6-dibromoaniline;4,6-Dibromo-m-toluidine

Chemical Property of 3-Methyl-4,6-dibromoaniline

Chemical Property:

• Melting Point: 75 °C
• Boiling Point: 284.0±35.0 °C(Predicted)
• PKA: 1.95±0.10(Predicted)
• PSA: 26.02000
• Density: 1.887±0.06 g/cm3(Predicted)
• LogP: 3.68340

Purity/Quality:

99% ^*data from raw suppliers

2,4-DIBROMO-5-METHYLANILINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-Methyl-4,6-dibromoaniline

There total 9 articles about 3-Methyl-4,6-dibromoaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

→ 2,4-dibromo-5-methylaniline (67643-51-0)

Guidance literature:

With sodium persulfate; sodium bromide; In water; at 20 ℃; for 5h; Irradiation;

Reference yield: 3.0%

1-amino-3-methylbenzene (108-44-1) → amino-5-bromo-2-toluene (6933-10-4) + 2,4-dibromo-5-methylaniline (67643-51-0) + 2,4-dibromo-3-methylaniline (80948-78-3) + 3-methyl-2,4,6-tribromoaniline (71642-16-5)

Guidance literature:

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In chloroform; at 20 ℃; for 0.5h; Solvent; Temperature;

Reference yield:

amino-5-bromo-2-toluene (6933-10-4) → 2,4-dibromo-5-methylaniline (67643-51-0) + 2,4-dibromo-3-methylaniline (80948-78-3)

Guidance literature:

With N-Bromosuccinimide; acetic acid; at 5 - 20 ℃; for 2h;

upstream raw materials:

3-Methylacetanilide

N-(2,4-dibromo-5-methylphenyl)acetamide

1,5-dibromo-2-methyl-4-nitrobenzene

hydrogenchloride

Downstream raw materials:

2,4-dibromo-5-methylphenol

2,4-dibromotoluene

2,4,5-tribromotoluene

N-(2,4-dibromo-5-methylphenyl)acetamide

Refernces

• 1、 -. "Method of catalytically synthesizing polybromo-aniline in water phase". Paragraph 0012; 0024. . Retrieved 2019/10/04.
• 2、 -. "BENZIMIDAZOLE ANTIVIRAL AGENTS". Page/Page column 131. . Retrieved 2011/09/14.