N-(4-bromophenyl)-4-methylbenzenesulfonamide

Base Information

• Chemical Name: N-(4-bromophenyl)-4-methylbenzenesulfonamide
• CAS No.: 32857-48-0
• Molecular Formula: C13H12BrNO2S
• Molecular Weight: 326.214
• Hs Code.: 2935009090
• Mol file: 32857-48-0.mol

Synonyms:N-(4-Bromophenyl)-4-methyl-benzenesulfonamide;(4-Bromophenyl)[(4-methylphenyl)sulfonyl]amine;N-(4-Bromo-phenyl)-4-methyl-benzenesulfonamide;

Chemical Property of N-(4-bromophenyl)-4-methylbenzenesulfonamide

Chemical Property:

• Vapor Pressure: 1.19E-07mmHg at 25°C
• Refractive Index: 1.642
• Boiling Point: 431.5 °C at 760 mmHg
• Flash Point: 214.8 °C
• PSA: 54.55000
• Density: 1.545 g/cm³
• LogP: 4.71210

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N-(4-bromophenyl)-4-methylbenzenesulfonamide

There total 15 articles about N-(4-bromophenyl)-4-methylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

p-toluenesulfonyl chloride (98-59-9) + 4-bromo-aniline (106-40-1) → N-(4-bromophenyl)-4-methylbenzenesulfonamide (32857-48-0)

Guidance literature:

With pyridine; In dichloromethane; for 2h; Inert atmosphere;

DOI:10.1002/anie.201306727

Reference yield: 97.0%

toluene-4-sulfonic acid hydrazide (1576-35-8) + 4-bromo-aniline (106-40-1) → N-(4-bromophenyl)-4-methylbenzenesulfonamide (32857-48-0)

Guidance literature:

toluene-4-sulfonic acid hydrazide; With N-chloro-succinimide; In acetonitrile; at 20 ℃; for 2h;

4-bromo-aniline; With triethylamine; at 20 ℃; for 2h;

DOI:10.3390/molecules26185551

Reference yield: 92.0%

toluene-4-sulfonic acid (104-15-4) + 4-bromo-aniline (106-40-1) → N-(4-bromophenyl)-4-methylbenzenesulfonamide (32857-48-0)

Guidance literature:

toluene-4-sulfonic acid; With N-chlorobenzotriazole; triphenylphosphine; In dichloromethane; at 0 - 20 ℃; for 0.25h;

4-bromo-aniline; With triethylamine; at 20 ℃; for 1.5h;

DOI:10.1080/10426507.2015.1024313

upstream raw materials:

p-toluenesulfonyl chloride

4-bromo-aniline

phenyl toluenesulfonamide

1,4-bromoiodobenzene

Downstream raw materials:

N-(4-Bromo-phenyl)-4-methyl-N-(2-methyl-allyl)-benzenesulfonamide

1,5-bis-[4-bromo-N-(toluene-4-sulfonyl)-anilino]-pentane

N-(4-(diphenylphosphoryl)phenyl)-4-methylbenzenesulfonamide

Refernces

• 1、 Zhang, Chenlu,Zhu, Hai,Gang, Kaiyue,Tao, Minli,Ma, Ning,Zhang, Wenqin. "Immobilization of copper(II) into polyacrylonitrile fiber toward efficient and recyclable catalyst in Chan-Lam coupling reactions". . . Retrieved 2021/02/09.
• 2、 Daniliuc, Constantin G.,Gilmour, Ryan,Neufeld, Jessica,Sarie, Jér?me C.,Thiehoff, Christian. "Enantioselective Synthesis of 3-Fluorochromanes via Iodine(I)/Iodine(III) Catalysis". supporting information. p. 15069 - 15075. Retrieved 2020/06/17.