BROMOACETIC ACID, [1-14C]

Base Information

• Chemical Name: BROMOACETIC ACID, [1-14C]
• CAS No.: 4561-21-1
• Molecular Formula: C2H3BrO2
• Molecular Weight: 140.97
• Mol file: 4561-21-1.mol

Synonyms:BROMO[1-14C]ACETIC ACID;BROMOACETIC ACID-CARBOXY-14C;BROMOACETIC ACID, [1-14C];bromoacetic-carboxy-C14-acid

Chemical Property of BROMOACETIC ACID, [1-14C]

Chemical Property:

• PSA: 37.30000
• LogP: 0.46590
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

BROMOACETIC ACID[1-14C] 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): T,C,R,N
• Hazard Codes: T,C,R,N
• Statements: 23/24/25-35-50
• Safety Statements: 26-36/37/39-45-61

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BROMOACETIC ACID, [1-14C]

There total 2 articles about BROMOACETIC ACID, [1-14C] which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

14C-acetic acid (2845-03-6) → [1-14C]bromoacetic acid (4561-21-1)

Guidance literature:

With phosphorus; bromine; at 125 ℃; for 2h;

DOI:10.1002/(SICI)1099-1344(199707)39:7<559::AID-JLCR4>3.0.CO;2-3

Reference yield:

→ [1-14C]bromoacetic acid (4561-21-1)

Guidance literature:

DOI:10.1007/BF00757828

Reference yield: 76.0%

[1-14C]bromoacetic acid (4561-21-1) + 2-[bis(4-chlorophenyl)methoxy]ethanethiol (400838-24-6) → 2-[bis(4-chlorophenyl)methoxy]ethylthio[1-14C]acetic acid

Guidance literature:

With sodium hydroxide; In tetrahydrofuran; ethanol; at 22 ℃; for 1h;

DOI:10.1002/jlcr.655

upstream raw materials:

¹⁴C-acetic acid

Downstream raw materials:

ethylbromoacetate-1-¹⁴C

bromo[1-⁽¹⁴⁾C]acetyl chloride

Refernces

• 1、 Szammer,Simon-Trompler,Mate,Abermann,Uermoes,Klebovich. "Synthesis of deramciclane labelled with radiocarbon in various positions". . p. 1011 - 1018. Retrieved 1997.