Technology Process of 4-acetylaMino-3-hydroxy-benzoic acid Methyl ester
There total 7 articles about 4-acetylaMino-3-hydroxy-benzoic acid Methyl ester which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
methyl 3-hydroxy-4-nitrobenzoate;
With
hydrogen;
palladium 10% on activated carbon;
In
tetrahydrofuran;
With
acetic anhydride;
In
water;
at 65 ℃;
for 0.5h;
- Guidance literature:
-
With
tetrabutyl ammonium fluoride;
In
tetrahydrofuran;
at 0 ℃;
for 1h;
Inert atmosphere;
DOI:10.1021/acs.orglett.8b03913
- Guidance literature:
-
methyl 3-hydroxy-4-nitrobenzoate;
With
palladium on activated charcoal; hydrogen;
In
tetrahydrofuran;
at 50 ℃;
for 3h;
Inert atmosphere;
acetyl chloride;
With
triethylamine;
In
tetrahydrofuran;
at 25 ℃;
for 16h;
Inert atmosphere;
With
triethylamine;
In
methanol;
at 25 ℃;
for 16h;
Inert atmosphere;